Canadian Treatment Guidelines on Psychosocial Treatment of Schizophrenia in Children and Youth

Lecomte, Tania; Abidi, Sabina; Garcia-Ortega, Iliana; Mian, Irfan; Jackson, Kevin T.; Norman, Ross

doi:10.1177/0706743717720195

Cited by 23 publications

(15 citation statements)

References 30 publications

(30 reference statements)

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“…Intervention components were developed based on feedback from a survey of youth in the same EPI programme, 30 as well as psychosocial interventions with evidence in early psychosis, including cognitive-behavioural therapy (psychoeducation, behavioural activation) and illness self-management (reminders, distress check-in). 31 32 See online supplemental file 1 for a comprehensive description of the intervention. Messages sent back by participants will be monitored by the research team, and the case manager assigned to their consultation appointment will be notified and will respond accordingly if there are indicators of elevated distress.…”

Section: Methods and Analysismentioning

confidence: 99%

ED to EPI: protocol for a pragmatic randomised controlled trial of an SMS (text) messaging intervention to improve the transition from the emergency department to early psychosis intervention for young people with psychosis

et al. 2020

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IntroductionWhile nearly half of all new psychotic disorders are diagnosed in the emergency department (ED), most young people who present to the ED with psychosis do not receive timely follow-up with a psychiatrist, and even fewer with evidence-based early psychosis intervention (EPI) services. We aim to test an intervention delivered using short message service (SMS), a low-cost, low-complexity, youth-friendly approach, to improve transitions from the ED to EPI services.Methods and analysisThis is a protocol for a pragmatic randomised, single blind, controlled trial with accompanying economic and qualitative evaluations conducted at the Centre for Addiction and Mental Health (CAMH) in Toronto, Canada. A consecutive series of 186 participants aged 16–29 referred by the ED to CAMH’s EPI programme will be recruited for a trial of a two-way intervention involving reminders, psychoeducation and check-ins delivered via SMS. The primary outcome will be attendance at the first consultation appointment within 30 days of study enrolment assessed through chart reviews in the electronic health record. We will also extract routine clinical measures, including the Brief Psychiatric Rating Scale, Clinical Global Impression and Service Engagement Scale, and link with provincial health administrative data to examine system-level outcomes, including ED visits and psychiatric hospitalisations, 6 months and up to 2 years after baseline. We will perform a cost-effectiveness analysis of the primary study outcome and costs incurred, calculating an incremental cost effectiveness ratio. Web-based surveys and qualitative interviews will explore intervention user experience. Patients and families with lived experience will be engaged in all aspects of the project.Ethics and disseminationResearch Ethics Board approval has been obtained. Findings will be reported in scientific journal articles and shared with key stakeholders including youth, family members, knowledge users and decision makers.Trial registration numberNCT04298450.

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Section: Methods and Analysismentioning

confidence: 99%

ED to EPI: protocol for a pragmatic randomised controlled trial of an SMS (text) messaging intervention to improve the transition from the emergency department to early psychosis intervention for young people with psychosis

et al. 2020

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“…La TCC est soutenue empiriquement par de multiples méta-analyses 6 et la TCCp est recommandée par le guide de l'Association canadienne de psychiatrie pour le traitement de la schizophrénie 7 . En plus d'une formation plus brève pour l'équipe, la TCCp de groupe a été jugée préférable dans un contexte SIM, car elle permet aux participants souvent isolés de socialiser ; elle peut être offerte en co-thérapie avec le soutien d'un pair aidant et elle favorise l'apprentissage interpersonnel.…”

Section: Thérapie Cognitive Comportementale Pour La Psychose (Tccp)unclassified

Stratégies d’engagement, faisabilité et impact potentiel d’une intervention de groupe cognitive comportementale pour la psychose au sein d’une équipe de suivi intensif dans le milieu

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Samson

et al. 2018

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Objectifs Le but de cette étude pilote est de documenter les stratégies utilisées pour faciliter l’engagement des participants d’une équipe de suivi intensif dans le milieu (SIM) à une thérapie cognitive comportementale pour la psychose (TCCp) de groupe offerte pour la première fois dans ce contexte, ainsi que de décrire la faisabilité de cette intervention auprès de ce type de clientèle et des intervenants impliqués. Méthode Une TCCp de groupe de 24 rencontres a été mise en place. Les participants ont été recrutés parmi les deux équipes SIM de Laval. Différentes stratégies ont été élaborées et documentées afin de favoriser l’engagement à la thérapie des participants. Les participants ont rempli les questionnaires suivants : l’Échelle brève d’estime de soi ; l’Inventaire bref des symptômes psychiatriques ; l’Échelle de provisions sociales avant et après la thérapie. Résultats Les données descriptives montrent que les stratégies faisant partie de la catégorie « Renforcements positifs » ont été les plus utilisées, étant suivies de près par les « Matériels et services » et ensuite par les stratégies visant à pallier les « Problèmes de mémoire ». Les participants se sont présentés en moyenne à 76 % des séances. Quatre participants sur huit ont eu une amélioration sur leur score global d’estime de soi, 3 se sont améliorés sur leur soutien social et 3 se sont améliorés au niveau de l’indice de sévérité globale des symptômes. Conclusion L’information recueillie pourrait être très importante pour d’autres équipes de suivi intensif qui souhaiteraient effectuer une TCCp au sein de la clientèle ciblée. Celle-ci pourrait particulièrement en bénéficier en considérant qu’une TCCp de groupe pourrait diminuer l’isolement social et la marginalisation souvent vécus par les individus ayant des troubles mentaux graves.

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“…However, children and adolescents are in a special stage of growth and development, and many factors, such as efficacy, safety and acceptability, need to be considered during drug treatment. Atypical antipsychotics have proven to be safer and more effective, so they gradually have become the first-line drugs in the treatment of schizophrenia in children and adolescents [ 4 , 5 ]. For example, a meta-analysis [ 6 ] that included randomized controlled studies between 1967 and 2017 showed that aripiprazole, olanzapine, risperidone, paliperidone and quetiapine have a significantly better therapeutic effect on patients with early-onset schizophrenia than placebo and that paliperidone, risperidone, olanzapine and quetiapine are somewhat better accepted than placebo.…”

Section: Introductionmentioning

confidence: 99%

Analysis of the status of drug treatment in 746 inpatients with early-onset schizophrenia in China: a retrospective study

et al. 2021

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Background There is limited evidence on the use of antipsychotics in patients with early-onset schizophrenia, which lags significantly behind the studies on adult patients’ medication and has a large disparity from actual clinical needs. Hence, this study aims to analyse the status of the drug use and its changes for patients with early-onset schizophrenia in our ward and to provide references on clinical medications for children and adolescents with schizophrenia. Methods The distribution of antipsychotics on the day of discharge and their changes over time were retrospectively analysed in our inpatient department from March 2012 to July 2019. Descriptive statistical methods and χ2 tests were carried out. Results A total of 746 inpatients with early-onset schizophrenia were included. Among them, 99.3% of patients were prescribed atypical antipsychotic drugs, with 5.5% of patients prescribed typical antipsychotic drugs. The top five most commonly used antipsychotics were aripiprazole, olanzapine, risperidone, paliperidone and clozapine. Olanzapine and risperidone were used more frequently in men (P < 0.01), whereas aripiprazole was used less frequently (P < 0.01). Olanzapine and paliperidone were used more frequently in patients with adolescent-onset schizophrenia (AOS) (P < 0.05), and risperidone was used more frequently in patients with child-onset schizophrenia (COS) (P < 0.01). Multiple antipsychotics during hospitalization were prescribed in 23.1% of patients. The combination of aripiprazole and olanzapine was the most common in the AOS group, and the combination of risperidone and clozapine was the most common in the COS group. Before and after approval by the competent Chinese authorities, the use of paliperidone and aripiprazole tended to be stable. Conclusion Atypical antipsychotics have been increasingly valued and used clinically. The consideration of medications for patients with early-onset schizophrenia needs to include factors such as age, sex, and severity of illness, metabolism and cognitive function at baseline.

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Canadian Treatment Guidelines on Psychosocial Treatment of Schizophrenia in Children and Youth

Cited by 23 publications

References 30 publications

ED to EPI: protocol for a pragmatic randomised controlled trial of an SMS (text) messaging intervention to improve the transition from the emergency department to early psychosis intervention for young people with psychosis

ED to EPI: protocol for a pragmatic randomised controlled trial of an SMS (text) messaging intervention to improve the transition from the emergency department to early psychosis intervention for young people with psychosis

Stratégies d’engagement, faisabilité et impact potentiel d’une intervention de groupe cognitive comportementale pour la psychose au sein d’une équipe de suivi intensif dans le milieu

Analysis of the status of drug treatment in 746 inpatients with early-onset schizophrenia in China: a retrospective study

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