Can We Use Serum Gamma-Glutamyl Transferase Levels to Predict Early Mortality in Stroke?

Akıncı, Emine; Doğan, Nurettın Özgür; Gümüş, Haluk; Akıllı, Nazire Belgin; Çevik, Yunsur

doi:10.1016/j.jemermed.2013.11.022

Cited by 1 publication

(1 citation statement)

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“…However, there have not been many studies evaluating the relationship of GGT levels with former smoking. 10,11 Many studies have shown that serum GGT is a biomarker of increased alcohol consumption, however, GGT is known to be affected beside previous condition, such as smoking, obesity, and hepatic steatosis. 12 Data is gathering that higher serum GGT levels may be associated with an increased incidence of cardiovascular events, metabolic syndrome and diabetes; therefore, more attention has been paid recently to this liver enzyme.…”

Section: Discussionmentioning

confidence: 99%

Effect of tobacco smoking on the enzymatic activity of serum gamma-glutamyltransferase

Thakkar¹,

Panchiwala²

2021

IJIRM

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Background : There have not been many studies evaluating the relationship of Gamma-glutamyltransferase (GGT) levels with former smoking and it is still not clear whether the effect is independent of alcohol drinking. This study was performed to evaluate the association between smoking status and serum GGT concentration. Methodology : One hundred and twenty participants were incorporated in the research. All the subjects were separated into 2 groups. Group 1 consist of 60 volunteers with habit of smoking. Group 2 consist of 60 volunteers without the habit of smoking. Four to 6 ml venous blood was reserved from all character by disposable syringes. The samples were instantly centrifuged for (10) minutes at 3000 round per minute, and the serum gained was analysed straight. Results: The findings specified that the smoker group classify as moderate smoker group. The findings acquired specified that the mean serum GGT activity was (23.49 ± 3.39 IU/L), in smokers group. This value was superior significantly to that acquired in non-smokers group (12.92 ± 2.73 IU/L) (p<0.003). Conclusions : Significant augmented action of GGT in smokers appears to sustain the injurious effects of cigarette smoking. Supplementary findings are essential to explain the alliance among dietary and existence factors and serum GGT activity.

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Section: Discussionmentioning

confidence: 99%