Laparoscopic cholecystectomy (LC) is a widely performed procedure worldwide, and it is one of the safest surgical interventions, with few short-and long-term complications. The presentation of post-LC acute pancreatitis (AP) is quite rare and with few reports over time. This case report relates the case of a 34-year-old woman who, 12 days after surgery, presented with AP with no other apparent cause, in addition to which a right renal mass was found incidentally. This case presents us with a rare complication of a fairly safe surgical procedure; however, it should serve to carry out a good follow-up of postoperative patients in the first weeks above all in order to prevent complications.