Can We Distinguish Between Benign Versus Malignant Compression Fractures of the Spine by Magnetic Resonance Imaging?

An, Howard S.; Andreshak, Thomas G.; Nguyen, Cahn; Williams, Alan L.; Daniels, David L.

doi:10.1097/00007632-199508150-00005

Cited by 104 publications

(48 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…It is advocated that evaluation of the posterior ligamentous complex on MRI is essential before a decision of instability is made. Compression fractures or burst fractures with middle-column involvement can be described as unstable if there is associated posterior ligamentous complex injury proven by MRI [1,18,20]. The most common fracture type in our patients was compression fracture.…”

Section: Discussionmentioning

confidence: 76%

Conservative treatment of fractures of the thoracolumbar spine

Tezer

Ertürer

Öztürk

et al. 2005

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

We reviewed 48 patients with thoracolumbar fractures treated conservatively between 1988 and 1999. The average follow-up was 77.5 (31-137) months and average patient age (23 women, 25 men) was 46 (18-76) years. Twenty-nine patients suffered a fall from a height and 13 patients were injured in traffic accidents. Thirty-two patients had compression-type fractures and 16 bursttype fractures. There were no neurological deficits. Twentynine patients were treated by orthosis, 13 by body cast and six by bed rest. In addition to pain and functional scoring, we measured a number of radiographic parameters at the time of admission and at latest follow-up and compared the values. In patients with compression fractures there were significant changes in scoliosis angle and wedging index (p<0.05). The mean pain score was 1.66 and mean functional score 1.03. In patients with burst fractures, vertebral index, wedging index and height loss increased after treatment (p<0.05). The mean pain score was 1.26 and functional score 0.93. Compression fractures with kyphosis angle <30°are supposed to be stable and can be treated conservatively. If the kyphosis angle is more than 30°, magnetic resonance imaging (MRI) should be performed, and if the posterior ligamentous complex is damaged, surgery should be considered. In burst fractures, MRI should always be performed and conservative treatment should only be considered if there is no neurological deficit and the ligaments are intact.

show abstract

Section: Discussionmentioning

confidence: 76%

Conservative treatment of fractures of the thoracolumbar spine

Tezer

Ertürer

Öztürk

et al. 2005

International Orthopaedics (SICOT)

View full text Add to dashboard Cite

show abstract

“…However, in certain cases these pre-operative investigations fail to provide correct diagnosis of the condition (4,10,11). It has been reported that the rate of distinguishing benign and malignant compression fractures of the spine through MRI is between 55 and 94% (13)(14)(15). Therefore, patients with malignancy require accurate pathological diagnosis to select the correct program for further treatment of their condition.…”

Section: Discussionmentioning

confidence: 99%

Histological evaluation of bone biopsy results during PVP or PKP of vertebral compression fractures

Zhang¹,

LI²,

Yang³

et al. 2012

Oncology Letters

View full text Add to dashboard Cite

Abstract. Percutaneous vertebroplasty (PVP) or percutaneous kyphoplasty (PKP) is utilized for the treatment of vertebral compression fractures (VCFswith a history of malignancy, malignancy was identified in 25 patients, while osteoporosis was identified in 16 patients. Biopsies of the other 3 patients were not suitable for pathological examination. There were only 2 patients with previously undiagnosed malignancy. One patient was diagnosed with multiple myeloma, while another patient was diagnosed with metastatic carcinoma. In the present study, the rate of unsuspected malignancy was 0.4%. No symptomatic complications occurred as a result of biopsy. The results indicate that biopsy is safely performed during PVP or PKP and it is an efficacious procedure that verifies the pathological process and assists in identifying previously unsuspected processes responsible for VCFs. We recommend obtaining the biopsy of every collapsed vertebral body during PVP or PKP procedures.

show abstract

“…9 The knowledge of pathology of these lesions will help in subsequent treatment. The rates of unsuspected malignancy on percutaneous biopsy range from 0.4% to 7.3%.…”

Section: Discussionmentioning

confidence: 99%

Fluroscopic guided percutaneous transpedicular biopsy of vertebral body lesion: a safe and effective procedure

et al. 2017

View full text Add to dashboard Cite

Background: Vertebral biopsy is suitable for patients with intractable back pain and vertebral body lesions that are detected with noninvasive imaging modalities. Histologic confirmation is necessary for correct diagnosis and subsequent clinical management. Percutaneous biopsy is less invasive and cost-effective.Methods: Twenty three patients with history of severe back pain with vertebral body lesion identified by any of computed tomography (CT) or magnetic resonance imaging (MRI) were taken up for percutaneous biopsy. Lesion level was determined under fluoroscopy. Biopsy was taken with trephine needle under local anesthesia. Accuracy and effectiveness analyzed after histologic reports.Results: Among 23 patients, 2 were having malignant primary lesions (8.6%), 8 were having vertebral metastasis (35%), 10 were having infectious etiology (43.4%) and 3 were osteoporotic fractures. There were no complications. One unsuspected secondary malignancy was detected. True positive cases were 19; true negative cases were 3 and one false negative case. Overall accuracy is 95%. Conclusions: This minimal invasive technique is simple, safe and effective in diagnosis of malignancy and infection aiding the treating surgeon in their further management. It is also useful in detecting unsuspected malignancy.

show abstract

Can We Distinguish Between Benign Versus Malignant Compression Fractures of the Spine by Magnetic Resonance Imaging?

Cited by 104 publications

References 0 publications

Conservative treatment of fractures of the thoracolumbar spine

Conservative treatment of fractures of the thoracolumbar spine

Histological evaluation of bone biopsy results during PVP or PKP of vertebral compression fractures

Fluroscopic guided percutaneous transpedicular biopsy of vertebral body lesion: a safe and effective procedure

Contact Info

Product

Resources

About