Can VAP-1 Protein be used as a Biomarker in Thyroid Cancer?

Baki, Ahmet; Tosun, Ilkay; Yıldız, Muhammet

doi:10.4274/imj.galenos.2019.26817

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Tumor-related Markers1

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2020

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“…58 Meanwhile, Baki's research in 2019 also confirmed its value as a potential marker. 59 Galectin-3 is a protein that binds to β-galactosyl residues of cell surface glycoproteins. Many studies have shown that its expression levels are different in benign and malignant thyroid tissues.…”

Section: Tumor-related Markersmentioning

confidence: 99%

<p>The Blood Biomarkers of Thyroid Cancer</p>

Wang¹,

Chang²,

Jia³

et al. 2020

CMAR

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Introduction: With the gradual increase in the incidence of thyroid cancer, people's attention to thyroid cancer has also gradually increased. Although the prognosis of thyroid cancer is rather mild compared to other cancers, it will still bring a heavy psychological burden on people who have been diagnosed. At present, the diagnosis of thyroid cancer mainly depends on ultrasound and percutaneous fine needle aspiration (pFNA). Due to the unsatisfactory accuracy of the diagnosis methods we use now, there are still some thyroid nodules that cannot be clearly diagnosed before surgery. Methods: In this article, we have searched for relevant research on blood markers of thyroid cancer in the past five years and categoried them into four groups. Discussion: Though we have not found a biomarker which can diagnose thyroid cancer both sensitively and specifically, we do found many substances that are related to it, and have the potential to recognize it and help the diagnosis. And perhaps combined models can do it better.

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Section: Tumor-related Markersmentioning

confidence: 99%