2014
DOI: 10.1055/s-0034-1390046 View full text |Buy / Rent full text
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Abstract: Clipping the TSC can cause histologic degeneration; however, histologic nerve regeneration occurs after unclipping.

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“…[8] In this electrophysiological study, we observed that the transmission of stimulation in the sympathetic nerve occurred again shortly after removal of the clip. In addition, in the histological results of our previous study, [6] the regenerative histological process and nerve conduction continued after the removal of the clip. Surgical intervention to T2 sympathetic nerve ganglion is widely used in the treatment of palmar hyperhidrosis.…”
Section: Discussionmentioning
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“…[8] In this electrophysiological study, we observed that the transmission of stimulation in the sympathetic nerve occurred again shortly after removal of the clip. In addition, in the histological results of our previous study, [6] the regenerative histological process and nerve conduction continued after the removal of the clip. Surgical intervention to T2 sympathetic nerve ganglion is widely used in the treatment of palmar hyperhidrosis.…”
Section: Discussionmentioning
“…In the treatment of primary hyperhidrosis, the nerve is clipped with titanium clips to prevent the conduction of sympathetic nerve stimulation. [6,7,11] In a study, although 11% of patients had relapse over a five-year period, the clinical outcomes were similar to resection (sympathectomy) or sympathetic chain transection (sympatheticotomy). [17] It is well documented that the use of metal clips is preferred over other methods, since it is theoretically thought that nerve stimulation can be achieved by removing the clips, when undesirable side effects develop.…”
Section: Discussionmentioning
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“…Although the mechanism of thoracic sympathetic chain regeneration is still not clear, sympathectomy and sympathicotomy are generally considered to be irreversible procedures due to the resection of sympathetic chain in contrast to other procedures as sympathetic clipping where the continuity of the sympathetic trunk is maintained. In an experimental study, Erol and colleagues [17] found a recovery of sympathetic nerve function after postsurgical removal of clips due to reconstitution of myelin, whereas no signs of sympathetic regeneration were found when the sympathetic chain was excised or remained clipped. Hemodynamic studies on patients who have undergone cardiac transplantation did not show any evidence of cardiac reinnervation up to 9 years after operation [18].…”
Section: Commentmentioning