Can the degree of retrograde diastolic flow in abnormal umbilical artery flow velocity waveforms predict pregnancy outcome?

Brodszki, Jana; Hernández‐Andrade, Edgar; Gudmundsson, Sæmundur; Dubiel, Mariusz; Mandruzzato, G. P.; Laurini, Ricardo; Maršál, Karel

doi:10.1046/j.1469-0705.2002.00636.x

Cited by 24 publications

(14 citation statements)

References 23 publications

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“…Vascular diseases due to preeclampsia, diabetes mellitus, renal disease or collagen vascular disease are the most common causes of IUGR [5,109]. There is good evidence from hemodynamic studies that the blood supply to the fetoplacental unit is imparied in preeclampsia and SGA and that physiological changes in the spiral arteries are restricted to the decidual segment in such cases [110].…”

Section: Diseases Of the Immune And Vascular System Including Preeclmentioning

confidence: 98%

Growth Restriction: Etiology, Maternal and Neonatal Outcome. A Review

Haram¹,

Svendsen²,

Myking

2007

CWHR

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Intrauterine growth restriction (IUGR) is an important clinical problem associated with increased perinatal mortality and morbidity. The most preferred small for gestational age (SGA) definition is birth weight below the 10th percentile, adjusted for gestational age. The incidence of IUGR is about 4 to 7 %. A variety of hormones are involved. IUGR may be due to chromosomal defects, smoking, early-onset preeclampsia (< 34 weeks), connective tissue and inflammatory rheumatic diseases, maternal infections, several drugs, twin-to twin transfusion, anorexia nervosa, low maternal pre-pregnancy or small weight gain during pregnancy. High hemoglobin (Hb) levels during the first 10-20 weeks of pregnancy may also cause IUGR. Complications due to IUGR include fetal or neonatal death, dysmaturity, and physical as well as temporary or permanent mental defects. Low birth weight children may have behavioral problems, psychiatric disorders and lower intelligence test scores later in life. There is a relationship between IUGR, timing and progression of puberty, and polycystic ovary syndrome. Fetal changes of lipid metabolism and homeostasis in IUGR may place the grown adult at risk for hypertension, diabetes mellitus and coronary artery disease. Mothers of low weight offspring have an increased risk for cardiovascular and kidney disease later in life.

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Section: Diseases Of the Immune And Vascular System Including Preeclmentioning

confidence: 98%

Growth Restriction: Etiology, Maternal and Neonatal Outcome. A Review

Haram¹,

Svendsen²,

Myking

2007

CWHR

View full text Add to dashboard Cite

show abstract

“…Such outcomes include the risk for stillbirth and neonatal death and the risk for peripartum acidemia and asphyxia, which have been related to poor neurodevelopment9, 10. Qualitative analysis of the UA waveform is easily accomplished and UA‐AREDV is predictive of critical short‐ and long‐term outcomes in IUGR fetuses11–14. The ability of venous Doppler to identify progressive fetal compromise has been demonstrated by several investigators5, 15–19.…”

Section: Introductionmentioning

confidence: 99%

Qualitative venous Doppler waveform analysis improves prediction of critical perinatal outcomes in premature growth‐restricted fetuses

Baschat

Gembruch

Weiner

et al. 2003

Ultrasound in Obstet & Gyne

130

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“…Various workers have noticed in fetuses with abnormal umbilical artery Doppler velocimetry, a similar poor perinatal outcome. 19,23,24 Mothers of small for gestational age babies with abnormal Doppler studies were more likely to have history of obstetric complications in the previous pregnancy as observed by McCown et al 19 They had high incidence of delivering small for gestational age babies, gestational hypertension, and history of perinatal death in the previous pregnancy.…”

Section: Discussionmentioning

confidence: 50%

“…25 Brodszki et al analyzed the outcome of 44 fetuses with REDF and found a perinatal mortality of 59%. 24 In a study on the role of umbilical artery Doppler to predict adverse perinatal outcome in women with preeclampsia Yoon et al 26 reported, that when gestational age at birth and pre-eclampsia were controlled for, an abnormal umbilical artery Doppler study was still a significant independent predictor of adverse perinatal outcome. Present study underlines the existence of a strict correlation between umbilical Doppler velocimetry and an increased incidence of perinatal complications in IUGR fetuses, in consonance with the study of Soregaroli et al 27 Similar results were drawn by Baschat et al when they looked at the umbilical artery resistance to determine Rashmi L et al Int J Reprod Contracept Obstet Gynecol.…”

Section: Discussionmentioning

confidence: 99%

Umbilical artery Doppler indices in relation to fetal outcome in high risk pregnancy

Bhattacharjee

2018

Int J Reprod Contracept Obstet Gynecol

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Background: Umbilical artery Doppler indices in relation to fetal outcome in high risk pregnancy. The aim of this study was to study the umbilical artery Doppler velocimetry in predicting the fetal outcome in high risk pregnancy. This is a prospective study done over a period of 1 year in Silchar Medical College and Hospital from 1st September 2011 to 31st August 2012. 100 women with singleton pregnancy with high risk admitted in SMCH were subjected to umbilical artery Doppler along with morphology and biometry scan after fulfilling the inclusion and exclusion criteria.Methods: 100 women with high risk pregnancy were evaluated by umbilical artery velocimetry between 28 and 41 weeks of pregnancy. Outcome of pregnancy was recorded for the normal Doppler group (n = 79; 79%), the low-end diastolic flow group (n = 19; 19%) and the group with absent/reversed diastolic flow (n = 2; 2%).Results: Mothers with abnormal velocimetry had more number of caesarean sections than those with normal velocimetry. The diagnosis to delivery interval, gestational age at delivery and average birth weight were comparatively lower with higher incidence of admission to neonatal intensive care unit in foetuses with abnormal umbilical Doppler velocimetry. Sensitivity, specificity, positive and negative predictive values of Doppler for detecting abnormal fetal outcome were 43%, 83%, 33% and 88% respectively. Statistical analysis used: sensitivity, specificity and predictive values.Conclusions: Fetuses with normal flow velocimetry are at lower risk than those with abnormal velocimetry in terms of poor Apgar score and neonatal intensive care admission. The average birth weight of the neonates with abnormal Doppler studies was lower than that of neonates with normal velocimetry. Doppler velocimetry studies of umbilical artery can provide the obstetrician important information regarding fetal wellbeing to help him improve fetal outcome.

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Can the degree of retrograde diastolic flow in abnormal umbilical artery flow velocity waveforms predict pregnancy outcome?

Abstract: The A/B or C/D ratio can be used for quantification of the reverse end-diastolic flow waveforms in the umbilical artery and may offer additional information to the evaluation of fetal condition.

Cited by 24 publications

References 23 publications

Growth Restriction: Etiology, Maternal and Neonatal Outcome. A Review

Growth Restriction: Etiology, Maternal and Neonatal Outcome. A Review

Qualitative venous Doppler waveform analysis improves prediction of critical perinatal outcomes in premature growth‐restricted fetuses

Umbilical artery Doppler indices in relation to fetal outcome in high risk pregnancy

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