Can Suicide Attempt be Related to Problem Drinking: Cohort Study

Dambrauskienė, Kristina; Adomaitienė, Virginija; Žalinkevičius, Rimantas; Jarienė, Giedrė; Vilkas, Vigintas; Rybakova, Ina; Dunderiene, Loreta

doi:10.1093/alcalc/agy080

Cited by 10 publications

(9 citation statements)

References 36 publications

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“…Similarly, the results showed that people with lower educational levels have a higher propensity to attempt suicide. Despite the lack of consensus on the association between education level and the risk of suicide attempt 30 , the results presented here corroborate previous studies 14 , 31 - 33 . A low education level is likely a marker of social disadvantage, which in turn is associated with various life stressors, including financial stress 11 , all of which are well-established associated factors 34 .…”

Section: Discussionsupporting

confidence: 88%

“…Alcohol consumption has also been reported as one of the main associated factors for suicidal behavior 42 . This association may be related to the effects of alcohol such as impulsivity, mood changes, and altered cognitive processes 30 . Alcohol consumption may also be related to the presence of psychiatric disorders that increase suicide attempts 43 .…”

Section: Discussionmentioning

confidence: 99%

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Suicide attempts in the adult Mexican population: an analysis of sociodemographic characteristics and associated factors

Davila-Cervantes,

Luna-Contreras

2024

Rev. bras. epidemiol.

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Objective: Suicide is the culmination of a process or continuum known as suicidal behavior that proceeds from ideation and planning to attempt. The objective was to estimate the prevalence of suicide attempts in the adult Mexican population and to analyze their main associated factors. Methods: We conducted an observational, cross-sectional, and descriptive study with information from the National Health and Nutrition Survey (2018). Self-reported lifetime suicide attempt was used in the analysis. We analyzed depression, obesity, tobacco smoking, and alcohol consumption as suicide attempt-associated factors using a multivariate logistic regression model. Results: The prevalence of adult suicide attempt was 2.0% (95%CI 1.8–2.2) and it was higher among women (2.4%; 95%CI 2.2–2.8) and young people (2.9%; 95%CI 2.4–3.4). Low education (OR=1.6; 95%CI 1.2–2.2), being single (OR=1.3; 95%CI 1.0–1.6), having obesity (OR=1.4; 95%CI 1.1–1.8), consumption of alcohol (OR=2.4; 95%CI 1.7–3.4) or tobacco smoking (OR=1.8; 95%CI 1.4–2.4), and having strong symptoms of depression (OR=10.1; 95%CI 6.2–16.3) were associated with a higher prevalence of suicide attempts. Conclusion: These results help better understand suicidal behavior in Mexico and identify the factors that increase the likelihood of suicide attempts, which is essential to help reduce suicide mortality. This research is crucial for developing early interventions and prevention programs aimed at reducing suicide's public health burden.

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Section: Discussionsupporting

confidence: 88%

Section: Discussionmentioning

confidence: 99%

Suicide attempts in the adult Mexican population: an analysis of sociodemographic characteristics and associated factors

Davila-Cervantes,

Luna-Contreras

2024

Rev. bras. epidemiol.

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“…We investigated the factors related to alcohol use only in patients who engaged in self-harm behaviors, and our results showed that the odds of consuming alcohol during or before self-harm behaviors increased with an increasing education level regardless of suicidal intent. Dambrauskiene et al [18] investigated the association between suicide attempts and al-cohol use disorders. They screened patients with drinking problems using the Cut down, Annoyed, Guilty, and Eyeopener (CAGE) questionnaire, which facilitated the diagnosis of alcohol use disorder.…”

Section: Suicide Attemptmentioning

confidence: 99%

“…Consistent with our findings, alcohol abuse or dependence was independently associated with being married (OR: 1.296; p = 0.0424) or living with someone (OR: 1.989; p = 0.0003). Furthermore, Dambrauskiene et al [18] reported that alcohol use disorder increased the risk of suicide attempts by 3.17 times in married individuals or those unmarried but living together. This could be attributed to patients with a family being more vulnerable to criticism or stigma if they have drinking problems.…”

Section: Suicide Attemptmentioning

confidence: 99%

Association between alcohol consumption and severity of self-harm behaviors based on suicidal intent in patients admitted to the emergency department for self-harm

2023

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This study aimed to investigate the association between alcohol consumption and the severity of self-harm behaviors based on the suicidal intents of patients admitted to the emergency department (ED) for self-harm. This was a retrospective study on patients admitted to the ED between March 2017 and December 2020 owing to self-harm behaviors and were grouped into a suicide attempt (SA) and non-suicidal self-harm (NSSH) group. A total of 642 (73.5%) and 232 (26.5%) patients were classified into SA and NSSH groups, respectively. In the SA group, 270 (42.1%) patients reported consuming alcohol, which was independently associated with ≥12 years of formal education and no history of psychiatric hospitalization. In the NSSH group, 87 (37.5%) patients reported consuming alcohol, which was associated with male sex, being married or unmarried but living together, ≥12 years of formal education, and no history of depression. Alcohol consumption could predict ED disposition in the SA group but not in the NSSH group. The impact of alcohol consumption varied according to suicidal intents among patients admitted to the ED for self-harm behavior. Regardless of suicidal intent, patients with a higher education level tended to drink alcohol when engaging in self-harm behaviors.

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“…According to the World Health Organization, 25-50% of suicide victims suffered from disorders associated with the use of alcohol and other psychoactive substances, while of all deaths from suicide 22% can be attributed to alcohol use [4]. In the cohort study conducted by Dambrauskiene K. and co-authors, 2/3 of the men and half of the women who committed suicide had problems with alcohol, the risk of suicide was also increased in alcohol abusers compared with drinkers within normal limits [5]. Similar results could be seen in population studies, while it is indicated that with the apparent linearity of the similarity, the relationship between such phenomena is more complex [6].…”

Section: Introductionmentioning

confidence: 99%

Association of single nucleotide variants rs34532313 of the <i>MTNR1A</i> gene and rs10830963 of the <i>MTNR1B</i> gene with suicidal risk in alcohol dependence syndrome and insomnia

Efremov

Asadullin

Akhmetova

et al. 2022

jour

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Background: Suicidal behaviour is the leading cause of mortality from external causes at all ages worldwide. More than a million people commit completed suicide each year. According to the World Health Organisation, 25-50% of suicide victims suffered from alcohol and other substance use disorders, 22% of all suicide deaths were attributable to alcohol use (WHO, 2014). Several papers have suggested potential associations of insomnia and increased suicide risk in patients with alcoholism. We hypothesise that mutations in melatonin receptor genes may be associated with suicide risk in patients with alcoholism.Methods. The Insomnia Severity Index (ISI) was used as a tool to assess the presence and severity of insomnia. The Columbia Suicide Severity Rating Scale (C-SSRS) was used as a method to examine suicidal behavior. Genotyping of MTNR1A (rs34532313), MTNR1B (rs10830963) genes was performed using real-time polymerase chain reaction (RT-PCR). A comparative genetic study of two groups of patients was carried out: the first group, patients with alcohol dependence syndrome (F10.2); the second group, patients with alcohol dependence syndrome (F10.2) and insomnia, which persisted 7-14 days after starting alcohol withdrawal therapy.Results. Suicidal thoughts and a history of auto-aggressive behaviour were more common in subjects with insomnia in the post-withdrawal period. Carriers of the TT genotype of the MTNR1A gene (rs34532313) were more likely to have suicidal thoughts and a history of suicide attempts in a genetic study of patients with insomnia.Conclusions. Our study found that the TT genotype of the MTNR1A gene (rs34532313) is a genetic marker of suicidal behaviour risk in patients with insomnia in the post-withdrawal period. However, the same pattern was not observed in patients without insomnia.

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Can Suicide Attempt be Related to Problem Drinking: Cohort Study

Cited by 10 publications

References 36 publications

Suicide attempts in the adult Mexican population: an analysis of sociodemographic characteristics and associated factors

Suicide attempts in the adult Mexican population: an analysis of sociodemographic characteristics and associated factors

Association between alcohol consumption and severity of self-harm behaviors based on suicidal intent in patients admitted to the emergency department for self-harm

Association of single nucleotide variants rs34532313 of the <i>MTNR1A</i> gene and rs10830963 of the <i>MTNR1B</i> gene with suicidal risk in alcohol dependence syndrome and insomnia

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