Can Pulmonary Hypertension and Increased Pulmonary Vascular Resistance Be Ruled in and Ruled Out by Echocardiography?

Bech‐Hanssen, Odd; Karason, Kristjan; Rundqvist, Bengt; Bollano, Entela; Lindgren, Fredrik; Selimovic, Nedim

doi:10.1016/j.echo.2013.02.011

Cited by 32 publications

(20 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…At the t vortex cut-off value of 14.3%, the sum of sensitivity and specificity was also consistently maximized in the receiver operating characteristic analysis for PH. The corresponding diagnostic performance parameters, which are substantially higher than those based on echocardiographic determination of tricuspid regurgitation (12,30), suggest PC MR imaging-based determination of vortex duration is an accurate noninvasive method for diagnosis of PH.…”

Section: Discussionmentioning

confidence: 96%

Blood Flow Vortices along the Main Pulmonary Artery Measured with MR Imaging for Diagnosis of Pulmonary Hypertension

et al. 2015

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 96%

Blood Flow Vortices along the Main Pulmonary Artery Measured with MR Imaging for Diagnosis of Pulmonary Hypertension

et al. 2015

View full text Add to dashboard Cite

show abstract

“…In addition, PAAT inversely correlated with HR in the healthy cohort and the ratio of systolic systemic/pulmonary arterial pressure in a smaller validation cohort of children with PH. As expected, the normative PAAT values in the adolescents were similar to adult PAAT reference data and above the adult normal cutoff value of 100 ms. [8][9][10][11] PAAT is the interval in ms from the onset of ejection to the peak flow velocity and is used for the estimation of PVR in adults. 7 Normative PAAT values in adults ranged from 136 to 153 ms. 9,11 The PAAT is affected not only by PAP, but also by pulmonary blood flow and pathological changes in the pulmonary vascular bed.…”

Section: Discussionmentioning

confidence: 99%

“…Indeed, PAAT seems to correlate with PAP and pulmonary vascular resistance (PVR). [7][8][9][10][11] A shorter PAAT suggests elevated PAP and PVR and, consequently, a larger afterload for right ventricular (RV) ejection. Lanzarini et al 12 found that a PAAT value <93 ms identified 67.4% of patients with pulmonary hypertension (PH).…”

mentioning

confidence: 99%

Normal Reference Values and z Scores of the Pulmonary Artery Acceleration Time in Children and Its Importance for the Assessment of Pulmonary Hypertension

Koestenberger

Grangl

Avian

et al. 2017

Circ: Cardiovascular Imaging

View full text Add to dashboard Cite

Background-Pulsed-wave Doppler determination of the pulmonary artery acceleration time (PAAT) as a surrogate for pulmonary artery pressure was found to be of clinical value for assessment of pulmonary hypertension (PH) with studies to date exclusively performed in adults. This study aims to provide representative, normal reference values for PAAT in children of all ages. Moreover, we validated abnormal PAAT values in 54 children with PH. Methods and Results-We conducted a prospective echocardiographic study in 756 healthy children (aged 1 day to 18 years) and in 54 children with PH. Possible associations of age, body length, body weight, body surface area, and heart rate on PAAT were investigated. The PAAT correlated positively with age (r=0.848), body length (r=0.871), body surface area (r=0.856), and body weight (r=0.825) and negatively with heart rate (r=−0.906). PAAT increased with age (neonates: median: 81 ms, range: 53-104; 18th year of life: median: 151 ms, range: 107-187). Receiver operating characteristic analysis for detecting PH patients using age-specific z scores showed an excellent performance of PAAT (P<0.001; area under the curve, 0.98; 95% confidence interval, 0.97-0.99) with a best cutoff score according to Youden index of -1.565 (sensitivity: 92%, specificity: 96%). PAAT values of PH patients negatively correlated (ρ=−0.497) with pulmonary vascular resistance. Conclusions-The PAAT normal reference values and z scores we provide here will be useful to identify children with a shortened PAAT. Abnormal PAAT values with scores <−2 were predictive of PH. (Circ Cardiovasc Imaging.

show abstract

“…Otherwise, echocardiography is effective for assessing pulmonary pressures and right ventricle function. There is a good relationship with between PVR calculated by ultrasound and by catheterization, and the PVR has been shown to be reliable by echocardiography …”

Section: Introductionmentioning

confidence: 85%

Can Pulmonary Vascular Resistance Predict Response to Cardiac Resynchronization Therapy in Patients with Heart Failure?

Zhang

Pan

et al. 2015

Pacing Clinical Electrophis

View full text Add to dashboard Cite

show abstract

Can Pulmonary Hypertension and Increased Pulmonary Vascular Resistance Be Ruled in and Ruled Out by Echocardiography?

Cited by 32 publications

References 34 publications

Blood Flow Vortices along the Main Pulmonary Artery Measured with MR Imaging for Diagnosis of Pulmonary Hypertension

Blood Flow Vortices along the Main Pulmonary Artery Measured with MR Imaging for Diagnosis of Pulmonary Hypertension

Normal Reference Values and z Scores of the Pulmonary Artery Acceleration Time in Children and Its Importance for the Assessment of Pulmonary Hypertension

Can Pulmonary Vascular Resistance Predict Response to Cardiac Resynchronization Therapy in Patients with Heart Failure?

Contact Info

Product

Resources

About