Can postoperative pains following tonsillectomy be relieved by honey?

Özlügedik, Samet; Genç, Selahattin; Ünal, Adnan; Elhan, Atilla Halil; Tezer, Mesut Sabri; Titiz, Ali

doi:10.1016/j.ijporl.2006.07.001

Cited by 59 publications

(18 citation statements)

References 38 publications

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“…Studies investigating the effects of honey on tonsillectomy included Tualang honey from Southeast Asia [20,18], unprocessed, pure honey from Malaysia [21], flower honey of thyme and tragacanth plants [16] and commercially available more or less undefined honey [17,29]. Several studies described, that honey application, even on inflamed oral mucosa, is a painless procedure [30,31].…”

Section: Discussionmentioning

confidence: 99%

“…The present study uses a standard honey (a blend of floral honey from EU and non-EU countries) provided by the University Hospital's kitchen for patient breakfast. The recommended frequency of oral honey application ranged from once [19] or three-times daily [20] to fourhourly [29] or even hourly intake during the waking phase [16]. Nevertheless, a clear recommendation for the application intervals cannot be deduced from these studies.…”

Section: Discussionmentioning

confidence: 99%

“…Honey might affect the local inflammation and thereby reduce und diminish duration of wound pain. The studies performed so far studying the effect of honey on postoperative pain after tonsillectomy revealed inconsistent results or did not used standard pain outcome measures [16,17,18,19,20,21,22,23,24,25].…”

Section: Introductionmentioning

confidence: 99%

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The effect of adjuvant oral application of honey in the management of postoperative pain after tonsillectomy in adults: A pilot study

et al. 2020

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Objective To analyze the effect of adjuvant oral application of honey for treating postoperative pain after tonsillectomy. Design Single centre prospective cohort study. Setting Two cohorts of patients after tonsillectomy. Participants 56 patients treated with honey 8 times per day (honey group), 18 patients treated without honey (control group); baseline analgesia were non-steroidal anti-inflammatory drugs (NSAID) or coxibs; opioids were used as pro re nata (PRN) medication; mean age 34.4 ± 13.4 years; 36% women. Main outcome measures On first to fifth postoperative day, patients rated their pain using the validated questionnaire of the German-wide project Quality Improvement in Postoperative Pain Treatment (QUIPS) including a numeric rating scale (NRS, 0-10) for determination of patient's pain. QUIPS allows standardized assessment of patients' characteristics andpain-associated patientreported outcomes (PROs). The influence of preoperative and postoperative parameters on patients' postoperative pain were estimated by univariate and multivariate statistical analysis.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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The effect of adjuvant oral application of honey in the management of postoperative pain after tonsillectomy in adults: A pilot study

et al. 2020

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“…These systems depend on the behavioural expression and/or verbal expression, and are sensitive for this population and validated measures of pain for children [4]. In addition, the frequency or amount of analgesics used following tonsillectomy used to be adopted as an objective criterion for assessment of pain [29]. This study attempted to assess the extent of pain via the observational pain scale as well as the frequency or amount of analgesics used.…”

Section: Discussionmentioning

confidence: 99%

Efficacy of Ketamine in Improving Pain after Tonsillectomy in Children: Meta-Analysis

et al. 2014

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Background and objectivesThe goal of this meta-analysis study was to perform a systematic review of the literature on the effects of ketamine on postoperative pain following tonsillectomy and adverse effects in children.Subjects and MethodsTwo authors independently searched three databases (MEDLINE, SCOPUS, Cochrane) from their inception of article collection to February 2014. Studies that compared preoperative ketamine administration (ketamine groups) with no treatment (control group) or opioid administration (opioid group) where the outcomes of interest were postoperative pain intensity, rescue analgesic consumption, or adverse effects (sedation, nausea and vomiting, bad dream, worsening sleep pattern, and hallucination) 0–24 hours after leaving the operation room were included in the analysis.ResultsThe pain score reported by the physician during first 4 hours and need for analgesics during 24 hours postoperatively was significantly decreased in the ketamine group versus control group and was similar with the opioid group. In addition, there was no significant difference between ketamine and control groups for adverse effects during 24 hours postoperatively. In the subgroup analyses (systemic and local administration) regarding pain related measurements, peritonsillar infiltration of ketamine was more effective in reducing the postoperative pain severity and need for analgesics.ConclusionPreoperative administration of ketamine systemically or locally could provide pain relief without side-effects in children undergoing tonsillectomy. However, considering the insufficient evaluation of efficacy of ketamine according to the administration methods and high heterogeneity in some parameters, further clinical trials with robust research methodology should be conducted to confirm the results of this study.

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“…The clinical applications of honey, particularly in the treatment of wounds, ulcers and burns are quite striking. It has been reported that honey promotes wound epithelization (Efem, 1993;Bergman, 1983;Efem, 1988;Subrahmanyam, 1988;Suguna, 1993), reduce inflammation (Subrahmanyam, 1998), edema (Efem, 1993;Efem, 1988;Gunther, 2010) and exudation (Efem, 1993;Efem, 1988), and accelerates synthesis of collagen and increase DNA content of the granulation tissue (Suguna, 1993;Lu et al, 2005;Ozlugedik, 2006;Koo et al, 2002;Park et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

Medical Dressing Treated with Honey/Chitosan Microencapsules

Elnagar

Nagi

El-Gamal

2012

IJC

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Wound normally left to dry and dressing keeps infections out as well as reducing the trauma. Advanced technology is used to reduce pain and fast healing with avoiding the deformation of the injured skin. In this work previously UV/ozone irradiated medical dressing samples were treated by honey capsulated in chitosan. Treatment conditions were optimized with respect to weight; air-permeability; whiteness; yellowness and antibacterial. All treated samples showed good antimicrobial performance with sufficient air permeability and weight. The sticky nature of the honey was avoided by formation of microencapsules. Treated gauze samples showed good performance for injured rates with no inflammation.

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Can postoperative pains following tonsillectomy be relieved by honey?

Cited by 59 publications

References 38 publications

The effect of adjuvant oral application of honey in the management of postoperative pain after tonsillectomy in adults: A pilot study

The effect of adjuvant oral application of honey in the management of postoperative pain after tonsillectomy in adults: A pilot study

Efficacy of Ketamine in Improving Pain after Tonsillectomy in Children: Meta-Analysis

Medical Dressing Treated with Honey/Chitosan Microencapsules

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