Can platelet indices be used as predictors of complication in subjects with appendicitis?

Abstract

Our findings suggested these, MPV values in cases of appendicitis without complication were lower than the cases with complication and healthy control and MPV is a predictor of the development of complication in subjects with appendicitis.

Is There a Supporting Value of Platelet Distribution Width and Plateletcrit in the Diagnosis of Acute Appendicitis in Children?

“…While there are many studies that have mainly focused on mean platelet volume (MPV), there are very few studies on other platelet indicators including PDW and PCT, especially in the pediatric age group. [2][3][4][5][6][7][8][9][10][11][12][13] PDW is an indicator of platelet volume variability in size, indicating morphological changes and platelet reactivity. The activation of platelets causes morphological changes that increase PDW.…”

“…While some of these studies have demonstrated a correlation between PDW and AA, others have reported no change in the value of PDW. 2,[7][8][9][10][11][12][13][14] Many of these studies have been conducted on adults, and only one has studied children. Dinc at al first reported that PDW may be a supportive parameter in the diagnosis of AA.…”

“…2 Furthermore, Ceylan et al and Kostakis et al determined that PDW levels did not change in acute or perforated appendicitis and control groups. 10,12 The diagnostic value of PDW on childhood appendicitis has only been evaluated by Yılmaz et al In a total of 224 children who underwent appendectomy, no appendicitis was seen in 20, and no difference in PDW level was reported between the two groups. In this study, there was also no significant difference in the PDW level between children with AA and healthy children.…”

Bedside Sonography Performed by Emergency Physicians to Detect Appendicitis in Children

“…The clinical diagnosis of appendicitis is challenging, especially in younger children who cannot verbalize their symptoms and in whom the physical examination is often unreliable . Laboratory studies and clinical scores, like the Alvarado score and the Pediatric Appendicitis Score, do not confer significant sensitivity or specificity to dictate management when used alone …”

Can Mean Platelet Volume be Used as a Marker in Children with Acute Appendicitis?

“…[10][11][12][13][14][15] AA'lı erişkinlerde OTH değişimiyle ilgili çalışmalar da giderek artmaktadır. [16][17][18][19][20][21][22] AA'lı çocuklarda OTH değişimini sorgulayan az sayıda çalışma vardır. [23][24][25] Bu çalışmada birincil olarak çocukluk yaş grubunda OTH'nin AA tanısındaki değerinin, ikincil olarak ise AA'da komplikasyon varlığının OTH değeri üzerine olan etkisinin araştırılması amaçlandı.…”