Can pattern electroretinography be a relevant diagnostic aid in amblyopia? – A systematic review

Fernandes, Andresa; Pinto, Nuno; Tuna, Ana Rita; Brardo, Francisco Miguel; Pato, Maria Vaz

doi:10.1080/08820538.2022.2069471

Cited by 2 publications

(2 citation statements)

References 40 publications

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“…There are three types of ERG: ffERG, multifocal ERG and pattern ERG. Full-field type is using special Ganzfeld bowl to illuminate retina, pattern type is working with highly contrasted checkerboard and multifocal ERG is based on evaluating macula with the use of multiple hexagons shapes [20][21][22].…”

Section: Physiological Electroretinography and Healthy Child Refractionmentioning

confidence: 99%

When a large refractive error is found in children, should we immediately order electroretinography?

Świątek

Pojda-Wilczek

2023

Ophthatherapy

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Electroretinography is a useful tool used in diagnosing retinal disorders. Refractive errors are a common and increasing group of abnormalities, which, if undiagnosed, may lead to complications. Physiologically, i.e., refraction of the child’s eye, evolves from myopic or hyperopic after birth, towards emmetropic. However, high refractive errors tend to present with retinal diseases. Early electroretinography is a great diagnostic test that allows its detection. Because of that, it can help avoid loss of eyesight and prevent future implications. Unfortunately, low accessibility and interpretational difficulties are main barriers in wider implementation of that method.

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Section: Physiological Electroretinography and Healthy Child Refractionmentioning

confidence: 99%

When a large refractive error is found in children, should we immediately order electroretinography?

Świątek

Pojda-Wilczek

2023

Ophthatherapy

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“…Early diagnosis and treatment help restore vision [2, 3]. Amblyopia results from a cortical visual imbalance, but retinal level changes may also be present [1, 4]. The anatomy and function of the retina in amblyopia have caught many scholars’ attention, and several studies involved these questions.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Retinal Microvascular Features in Patients with Amblyopia Based on Optical Coherence Tomography Angiography: A Systematic Review and Meta-Analysis

Feng

Zhang

et al. 2023

Ophthalmic Res

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Background: The performance of optical coherence tomography angiography (OCTA) in macular microvasculature of patients with amblyopia has been widely studied, but these studies have yielded different and controversial results. Objectives: To investigate retinal microvascular features in patients with amblyopia undergoing OCTA. Methods: PubMed, Embase, and Web of Science were searched for published articles comparing the retinal microvascular features between individuals with amblyopia and controls until April 2022. The mean difference with a 95% confidence interval was used to assess continuous variables. Results: The analysis included 17 studies. The whole vessel density of the superficial capillary plexus (SCPVD) was lower in amblyopic eyes (AE) than in normal control eyes (NE) in 3 × 3 mm2 scans, while the perifoveal vessel density of superficial and deep capillary plexus was lower in 6 × 6 mm2 scans. The whole parafoveal vessel density of deep capillary plexus (DCPVD) and parafoveal-SCPVD were lower in both scans. The comparison between amblyopic eyes and fellow eyes (FE) revealed no statistical difference in all quadrants except the parafoveal and perifoveal-SCPVD and the foveal-DCPVD. Additionally, SCPVD in all quadrants except the fovea and DCPVD in all quadrants except the parafoveal were higher in fellow eyes compared to normal control eyes. No significant difference was found in the foveal avascular area between AE and NE, AE and FE, or NE and FE. Conclusions: The retinal vessel density of superficial and deep capillary plexus in amblyopic and fellow eyes was lower than in normal controls, and differences were more likely discovered using 6 × 6 mm2 scans. Consequently, OCTA may be utilized as a diagnostic tool to identify and monitor patients with amblyopia.

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Can pattern electroretinography be a relevant diagnostic aid in amblyopia? – A systematic review

Cited by 2 publications

References 40 publications

When a large refractive error is found in children, should we immediately order electroretinography?

When a large refractive error is found in children, should we immediately order electroretinography?

Evaluation of Retinal Microvascular Features in Patients with Amblyopia Based on Optical Coherence Tomography Angiography: A Systematic Review and Meta-Analysis

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