Prospective Randomized Study edside emergency cardiac sonography is ideally suited to rule in or rule out poor left ventricular (LV) systolic function. 1 Overall cardiac function is important in making more accurate diagnoses and clinical care decisions. [1][2][3][4][5][6] Visual estimates of LV systolic function can differentiate severely depressed from normal LV systolic function, but physicians often encounter disagreements in differentiating moderately depressed and normal LV systolic function. [7][8][9] Quantitative comprehensive echocardiographic measAnthony J. Weekes, MD, Abhiram Reddy, MD, Margaret R. Lewis, MD, H. James Norton, PhD Received April 19, 2012,
ORIGINAL RESEARCHObjectives-Rapid bedside assessment of left ventricular (LV) function can aid in the evaluation of the critically ill patient and guide clinical management. Our primary hypothesis was that mitral valve E-point septal separation measurements would correlate with contemporaneous fractional shortening measurements of LV systolic function when performed by emergency physicians. Our secondary hypothesis was that E-point septal separation as a continuous variable would predict fractional shortening using a linear regression model.Methods-We studied a prospective convenience sample of patients undergoing a sequence of LV systolic function measurements during a 3-month period at a suburban academic emergency department with a census of 114,000 patients. The sample included adult emergency department patients who were determined by the treating emergency physician to have 1 or more clinical indications for bedside LV systolic function assessment. Investigators performed bedside M-mode cardiac sonographic measurements of fractional shortening and E-point septal separation using the parasternal long-axis window. The sequence of LV systolic function measurements was randomized.Results-A total of 103 patients were enrolled. The Pearson correlation coefficient for E-point septal separation and fractional shortening measurements was -0.59 (P < .0001). Linear regression analysis performed for E-point septal separation with fractional shortening as the dependent variable yielded an R 2 value of 0.35.Conclusions-E-point septal separation and fractional shortening measurements had a moderate negative correlation. E-point septal separation, when used as a continuous variable in a linear regression model, did not reliably predict fractional shortening.