Can inactive blood donors be re‐recruited? A stratified randomised pilot study

Ou-Yang, Jian; He, Bo; Xiao, Rong; Bei, Chunhua

doi:10.1111/tme.12436

Cited by 8 publications

(5 citation statements)

References 18 publications

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“…The calculated sample size needed for each group was 2252 [29], and in order to better detect significant differences and balance the sample size in each tier, the actual sample size was 3960 in each group (11,880 total). All participants were stratified into 18 tiers by age (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40), and 41-50 years), gender (male and female), and frequency of prior donation, which refers to number of times a donor donated before becoming inactive (one time, two or three times, and four times or more). Based on a computer-generated list of random numbers, the first 220 eligible participants in each tier were assigned to the telephone group, the 221st to 440th were assigned to the SMS group, and the 441st to 660th were assigned to the control group.…”

Section: Study Design Setting and Participantsmentioning

confidence: 99%

“…The experimental period lasted from October 20 to November 10, 2016. The details of the recruitment method were described in the pilot study [29]. The start time was set at the day that an intervention was made.…”

Section: Interventions and Endpointmentioning

confidence: 99%

“…The interviews were conducted using pre-designed questionnaires and lasted 2.4-21.3 min (mean ± SD, 4.8 ± 1.2 min). Prior to this study, the interviewers summarized the barriers to donation frequently mentioned by participants in the pilot study [29], discussed the challenges that arose during the interviews, reviewed the optimal response techniques, and practiced via role playing to ensure adherence to the script. Donors who could not be reached by telephone because the phone number was wrong were marked as non-responders.…”

Section: Telephone Call Remindermentioning

confidence: 99%

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Effective methods for reactivating inactive blood donors: a stratified randomised controlled study

et al. 2020

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Background Recruiting of sufficient numbers of donors of blood products is vital worldwide. In this study we assessed the efficacy and cost-effectiveness of telephone calls and SMS reminders for re-recruitment of inactive blood donors. Methods This single-centre, non-blinded, parallel randomised controlled trial in Guangzhou, China included 11,880 inactive blood donors whose last donation was between January 1 and June 30, 2014. The donors were randomly assigned to one of two intervention groups (telephone call or short message service [SMS] communications) or to a control group without intervention. SMS messages with altruistic appeal were adopted in the SMS group; in addition to altruistic appeal, reasons for deferral of blood donation were also asked in the telephone group. All participants were followed up for 1 year. The primary outcome was re-donation rate, and rates in different groups were compared by intention-to-treat (ITT) analysis and estimation of the average treatment effect on the treated (ATT). Secondary outcomes were the self-reported deterrents. Other outcomes included the re-donation interval, and the incremental cost-effectiveness ratio (ICER) of telephone calls and SMS reminders on re-recruitment. Results ITT analysis revealed no significant differences in the re-donation rate among the three groups. ATT estimations indicated that among compliers, telephone calls significantly increased re-donation compared to both SMS reminders and no intervention. Donor return behaviour was positively associated with receiving reminders successfully, being male, older age, and previous donation history. The SMS reminder prompted donors to return sooner than no reminder within 6 months, and according to ICER calculations, SMS reminders were more cost-effective than telephone calls. Donors reported time constraints as the most main causes of self-deferral in the telephone group, and altruistic appeal had a positive effect on these donors. Conclusions Interventions to reactivate inactive blood donors can be effective, with telephone calls prompting more donors to return but at a greater cost than SMS messages. SMS reminder with altruistic appeal can urge donors to re-donate sooner within 6 months than no reminder. Trial registration NCT03366441 (Reactivation of Inactive Blood Donors). Retrospectively registered 4 December 2017.

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Section: Study Design Setting and Participantsmentioning

confidence: 99%

Section: Interventions and Endpointmentioning

confidence: 99%

Section: Telephone Call Remindermentioning

confidence: 99%

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Effective methods for reactivating inactive blood donors: a stratified randomised controlled study

et al. 2020

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“…The calculated sample size needed for each group was 2,252 [29], and in order to better detect significant differences and balance the sample size in each tier, the actual sample size was 3,960 in each group (11,880 total). All participants were stratified into 18 tiers by age (20)(21)(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36)(37)(38)(39)(40), and 41-50 years), gender (male and female), and frequency of prior donation, which refers to number of times a donor donated before becoming inactive (one time, two or three times, and four times or more). Based on a computer-generated list of random numbers, the first 220 eligible participants in each tier were assigned to the telephone group, the 221 st to 440 th were assigned to the SMS group, and the 441 st to 660 th were assigned to the control group.…”

Section: Study Design Setting and Participantsmentioning

confidence: 99%

Effective methods for reactivating inactive blood donors: a stratified randomized controlled study

Ou-Yang¹,

Bei

LIANG

et al. 2019

Preprint

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Background: Recruiting of sufficient numbers of donors of blood products is vital worldwide. In this study we assessed the efficacy and cost-effectiveness of telephone calls and SMS reminders for rerecruitment of inactive blood donors. Methods: This single-centre, non-blinded, parallel randomized controlled trial in Guangzhou, China included 11,880 inactive blood donors whose last donation was between January 1 and June 30, 2014. The donors were randomly assigned to one of two intervention groups (telephone call or short message service SMS communications) or to a control group without intervention. SMS messages with altruistic appeal were adopted in the SMS group; in addition to altruistic appeal, reasons for deferral of blood donation were also asked in the telephone group. All participants were followed up for 1 year. The primary outcome was re-donation rate, and rates in different groups were compared by intention-to-treat (ITT) analysis and estimation of the average treatment effect on the treated (ATT). Secondary outcomes were the self-reported deterrents. Other outcomes included the re-donation interval, and the incremental cost-effectiveness ratio (ICER) of telephone calls and SMS reminders on re-recruitment. Results: ITT analysis revealed no significant differences in the re-donation rate among the three groups. ATT estimations indicated that among compliers, telephone calls significantly increased re-donation compared to both SMS reminders and no intervention. Donor return behaviour was positively associated with receiving reminders successfully, being male, older age, and previous donation history. The SMS reminder prompted donors to return sooner than no reminder within 6 months, and according to ICER calculations, SMS reminders were more cost-effective than telephone calls. Donors reported time constraints as the most main causes of self-deferral in the telephone group, and altruistic appeal had a positive effect on these donors. Conclusions: Interventions to reactivate inactive blood donors can be effective, with telephone calls prompting more donors to return but at a greater cost than SMS messages. SMS reminder with altruistic appeal can urge donors to re-donate sooner within 6 months than no reminder.

show abstract

Section: Study Design Setting and Participantsmentioning

confidence: 99%

Effective methods for reactivating inactive blood donors: a stratified randomized controlled study

Ou-Yang¹,

Bei

LIANG

et al. 2019

Preprint

View full text Add to dashboard Cite

Background: Recruiting of sufficient numbers of donors of blood products is vital worldwide. In this study we assessed the efficacy and cost-effectiveness of telephone calls and SMS reminders for re-recruitment of inactive blood donors. Methods: This single-centre, non-blinded, parallel randomized controlled trial in Guangzhou, China included 11,880 inactive blood donors whose last donation was between January 1 and June 30, 2014. The donors were randomly assigned to either one of two intervention groups (received telephone or short message service [SMS] communications) or to a control group without intervention. SMS messages with altruistic appeal were adopted in the SMS group; in addition to altruistic appeal, reasons for deferral of blood donation were also asked in the telephone group. All participants were followed up for 1 year. The primary outcome were re-donation rates, compared by intention-to-treat (ITT) analysis, average treatment effect (ATE) and average treatment effect on the treated (ATT) estimations. Secondary outcomes were the self-reported deterrents. Other outcomes included the re-donation interval, and the incremental cost-effectiveness ratio (ICER) of telephone calls versus SMS reminders on re-recruitment. Results: ITT analysis discovered no significant differences in the re-donation rate among the three groups. ATE estimation showed that participants who were randomly assigned to the telephone group were more likely to re-donate than those in the SMS group. ATT estimations indicated that among compliers, telephone calls significantly increased re-donation compared to both SMS reminders and no intervention. Donor return behaviour was positively associated with receiving reminders successfully, being male, older age, and previous donation history. The SMS reminder prompted donors to return sooner than no reminder within 6 months, and according to ICER calculations, SMS reminders were more cost-effective than telephone calls. Donors reported time constraints as the most main causes of self-deferral in the telephone group, and altruistic appeal had a positive effect on these donors. Conclusions: Interventions to reactivate inactive blood donors can be effective, with telephone calls prompting more donors to return but at a greater cost than SMS messages. SMS reminder with altruistic appeal can urge donors to re-donate sooner within 6 months than no reminder.

show abstract

Can inactive blood donors be re‐recruited? A stratified randomised pilot study

Abstract: Our findings suggest that active interventions, especially phone call reminders, can increase blood donation. Further studies are required to compare the efficacy and effectiveness between phone call and SMS reminders using a larger sample size.

Cited by 8 publications

References 18 publications

Effective methods for reactivating inactive blood donors: a stratified randomised controlled study

Effective methods for reactivating inactive blood donors: a stratified randomised controlled study

Effective methods for reactivating inactive blood donors: a stratified randomized controlled study

Effective methods for reactivating inactive blood donors: a stratified randomized controlled study

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