Can Emblica officinalis and Tinospora cordifolia supplementation possess immunomodulatory and adaptogenic properties in murrah buffalo calves?

Abstract

The present investigation was conducted to evaluate the combined effect of Emblica officinalis and Tinospora cordifolia supplementation on growth performance, hormonal and immune status in murrah buffalo calves. 14 day age unsupplementated 6 calves were taken as control, whereas 6 calves of treatment group were supplemented with combination of Emblica officinalis and Tinospora cordifolia (2:1) @ 450 mg/ kg body weight once a day orally for 28 days. The results indicated that, significant (p<0.05) higher body weight in treatment group as compare to control group. Serum cortisol concentration was significantly (p<0.05) lower in treatment group. Higher level of T 4 hormone, immunoglobulins and adaptability coefficient was observed in Emblica officinalis and Tinospora cordifolia treated group. It indicated that combination of Emblica officinalis and Tinospora cordifolia possess immunogenic effect and by inducing a state of non-specific increase in resistance to diverse climatic conditions they help to prevent calf mortality.

Recent Insights into the Morphological, Nutritional and Phytochemical Properties of Indian Gooseberry (Phyllanthus emblica) for the Development of Functional Foods

“…Patel et al [ 66 ] reported the effects of Tinospora cordifolia and Emblica officinalis supplementation on growth performance, immunological status, and hormonal condition in murrah calf buffalos. Six nonsupplemented calves at 14 days of age were used as the control group, whereas six calves in the treatment group received a combination of Tinospora cordifolia and Emblica officinalis (1:2) at the rate of 450 mg once a day for 28 days, based on bodyweight.…”

Thermal and nonthermal processing of an underutilized fruit Emblica officinalis (Amla): a sustainable approach

“…Fig. 2 shows different pharmacological effects of amla fruit including antidiabetic, 83,84 anti-inflammatory, 85,86 cardioprotective, 87,88 immunomodulator, 89 memory enhancer, 90 wound healer, 91 neuroprotector, 92,93 free radical scavenger, 94,95 eye protector, 96 antithyroidism, 97 antimicrobial, 98 and most important anticancer. 99,100 Amla can also be helpful in treating a plethora of diseases and disorders including hyperacidity, constipation, colitis, haemorrhoids, dyspepsia, gastritis, ophthalmic issues, anaemia, cough, asthma, osteoporosis, premature greying of hair, weakness and fatigue, nerve debility and liver complaints.…”