Can a plant-derived compound provide a lupus lifeline?

Marakkath, Bindiya; Mohan, Chandra

doi:10.2217/ijr.15.2

Cited by 1 publication

(1 citation statement)

References 24 publications

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“…Although novel approaches including anti-CD20 (B-lymphocyte antigen CD20) antibodies and calcineurin inhibitors have shown encouraging results, their long-term benefit/risk ratios have not been specified [ 26 ]. Hence, it would be desirable to provide treatments based on societal dietary and food with no side effects [ 27 ]. In fact, some of the foodstuffs can be used as functional food in the treatment of this disease [ 28 ].…”

Section: Introductionmentioning

confidence: 99%

Treatment of Lupus Nephritis from Iranian Traditional Medicine and Modern Medicine Points of View: A Comparative Study

Vahedi-Mazdabadi

Saeedi

2021

Evidence-Based Complementary and Alternative Medicine

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Objective. Nephritis or kidney inflammation is characterized as one of the most common renal disorders leading to serious damage to the kidneys. Nephritis, especially lupus nephritis (LN), has remained as the main cause of chronic renal failure which needs serious therapeutic approaches such as dialysis and kidney transplant. Heredity, infection, high blood pressure, inflammatory diseases such as lupus erythematosus and inflammatory bowel disease, and drug-related side effects are known as the main causes of the disease. According to Iranian traditional medicine (ITM), infectious diseases and fever are the main reasons of nephritis, which is called “Varam-e-Kolye” (VK). Results. There are various plant-based remedies recommended by ITM for the treatment of nephritis, as discussed herein, comparing with those available in the modern medicine. There is no definite cure for the treatment of nephritis, and immunosuppressive drugs such as corticosteroids and nonsteroidal anti-inflammatory drugs, antibiotics, diuretics, analgesics, and finally dialysis and kidney transplantation are usually used. Based on the efficacy of medicinal plants, jujube (Ziziphus jujuba), almond (Prunus amygdalus), pumpkin seeds (Cucurbita pepo), purslane (Portulaca oleracea), and fig (Ficus carica) were found to be effective for the treatment of kidney inflammation in ITM. Conclusion. Considering the fact that there is no efficient strategy for the treatment of nephritis, use of herbal medicine, particularly based on the fruits or nuts that have been safely used for several years can be considered as a versatile supplement along with other therapeutic methods.

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Section: Introductionmentioning

confidence: 99%