Campylobacter: pathogenicity and significance in foods

Butzler, Jean‐Paul; Oosterom, J.

doi:10.1016/0168-1605(91)90043-o

Cited by 112 publications

(53 citation statements)

References 22 publications

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“…Animals carrying Campylobacter pose a risk for human infections from contamination of carcasses, milk, and water through wastes and slurries [6][7][8][9]. Human illness, frequently associated with Campylobacter jejuni and Campylobacter coli, is characterized by watery to bloody diarrhoea, abdominal pain, fever, malaise, nausea, presence of leukocytes and red blood cells in faeces and/or vomiting [10,11]; and may persist for a week or even longer [12]. Campylobacter infections can also develop to Guillain-Barre´ syndrome (GBS), an autoimmune-mediated neurodegenerative disorder which causes acute neuromuscular paralysis [13,14].…”

Section: Introductionmentioning

confidence: 99%

Human and Animal Thermophilic Campylobacter infections in East African countries: Epidemiology and Antibiogram

Komba¹

2017

BJSTR

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Section: Introductionmentioning

confidence: 99%

Human and Animal Thermophilic Campylobacter infections in East African countries: Epidemiology and Antibiogram

Komba¹

2017

BJSTR

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“…Epidemiological surveillance and monitoring of Campylobacter jejuni, the major bacterial causative agent of diarrhoeal disease in man [5][6][7][8], has been based mainly on biotyping according to the schemes of Skirrow [9] and of Lior [10] and on the internationally recognized serotyping systems of Penner and Hennessy [11] and of Lior and coworkers [12]. Phage typing has been developed but utilized in only a limited number of studies on C. jejuni [13][14][15].…”

Section: Introductionmentioning

confidence: 99%

Molecular subtyping by genome and plasmid analysis ofCampylobacter jejuniserogroups O1 and O2 (Penner) from sporadic and outbreak cases of human diarrhoea

Fayos

Owen²,

Hernández³

et al. 1993

Epidemiol. Infect.

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SUMMARYRibosomal RNA gene patterns, randomly amplified polymorphic genomic DNA (RAPD) profiles and plasmid profiles were used to discriminate between 28 strains of Campylobacterjejuni serogroups 01 and 02 (Penner). Most isolates were biotype I (Lior). The strains were representative isolates from a UK school outbreak of enteritis (7 cases) and from 21 sporadic human cases of enteritis in 4 countries. The molecular techniques discriminated to various degrees between strains in each of the serogroups. The outbreak strains were homogeneous in most molecular features but a variety of types was detected amongst the isolates from the sporadic cases. Five groups of two or more strains with identical ribopatterns were identified and within each, strains from different patients were homogenous with respect to serogroup. RAPD profile typing based on numerical analysis generally matched ribotyping. Plasmid profiling overall gave least discrimination but was useful in separating some strains similar in other features. We concluded that optimal discrimination of C. jejuni could best be achieved using a combination of phenotypic and genotypic properties. Hae III ribotyping was the single most discriminatory and reproducible technique investigated. Several strains of C. jejuni from sporadic infections had similar molecular profiles which have potential for general typing purposes.

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“…The first explanation is that during the warmer summer months, human exposure to the pathogens increases through outdoor grilling. It is thought that this might reduce the likelihood of thorough cooking and also increase the possibility of cross-contamination on relatively crowded barbecue grills (35,37). A second explanation is seasonality in the number of animals with campylobacteriosis, which in turn drives the seasonality of human disease incidence (38).…”

Section: The Ecology Of Campylobacteriosismentioning

confidence: 99%

Pathogen survival trajectories: an eco-environmental approach to the modeling of human campylobacteriosis ecology.

Skelly

Weinstein²

2003

Environ Health Perspect

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Campylobacteriosis, like many human diseases, has its own ecology in which the propagation of human infection and disease depends on pathogen survival and finding new hosts in order to replicate and sustain the pathogen population. The complexity of this process, a process common to other enteric pathogens, has hampered control efforts. Many unknowns remain, resulting in a poorly understood disease ecology. To provide structure to these unknowns and help direct further research and intervention, we propose an eco-environmental modeling approach for campylobacteriosis. This modeling approach follows the pathogen population as it moves through the environments that define the physical structure of its ecology. In this paper, we term the ecologic processes and environments through which these populations move "pathogen survival trajectories." Although such a modeling approach could have veterinary applications, our emphasis is on human campylobacteriosis and focuses on human exposures to Campylobacter through feces, food, and aquatic environments. The pathogen survival trajectories that lead to human exposure include ecologic filters that limit population size, e.g., cooking food to kill Campylobacter. Environmental factors that influence the size of the pathogen reservoirs include temperature, nutrient availability, and moisture availability during the period of time the pathogen population is moving through the environment between infected and susceptible hosts. We anticipate that the modeling approach proposed here will work symbiotically with traditional epidemiologic and microbiologic research to help guide and evaluate the acquisition of new knowledge about the ecology, eventual intervention, and control of campylobacteriosis.

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Campylobacter: pathogenicity and significance in foods

Cited by 112 publications

References 22 publications

Human and Animal Thermophilic Campylobacter infections in East African countries: Epidemiology and Antibiogram

Human and Animal Thermophilic Campylobacter infections in East African countries: Epidemiology and Antibiogram

Molecular subtyping by genome and plasmid analysis ofCampylobacter jejuniserogroups O1 and O2 (Penner) from sporadic and outbreak cases of human diarrhoea

Pathogen survival trajectories: an eco-environmental approach to the modeling of human campylobacteriosis ecology.

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