Campylobacter jejuni prosthetic joint infection in an ulcerative colitis patient in the absence of gastrointestinal symptoms

Ali, Saqib; Siddiqui, Budder; Lawal, Folake

doi:10.1016/j.idcr.2020.e00920

Cited by 4 publications

(2 citation statements)

References 12 publications

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“…C. jejuni is an exceedingly rare cause of PJI and is thought to be the result of haematogenous seeding of the hardware due to bacteraemia. In published case reports detailing C. jejuni PJI, a significant portion of cases were not preceded by any GI symptoms 17. This was consistent with our patient’s presentation, although our patient did have chronic diarrhoea which may have obscured her acute GI symptoms.…”

Section: Discussionsupporting

confidence: 89%

Prosthetic hip infection due toCampylobacter jejuni

et al. 2022

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A woman in her 60s with a left hip prosthesis was presented with left hip pain and fever. She had an elevated white blood cell count and inflammatory markers. Synovial fluid Gram stain demonstrated curved Gram-negative rods identified as Campylobacter jejuni. The patient initially refused surgery and after 3 months underwent one-stage exchange after which she was treated with 12 weeks of levofloxacin. Her inflammatory markers normalised and she was clinically doing well at her 6-month follow-up. C. jejuni is a rare cause of prosthetic joint infection and should be included in the differential diagnosis when a patient has risk factors even without significant preceding gastrointestinal symptoms. Per most recent Infectious Diseases Society of America guidelines, treatment after one-stage revision includes 4–6 weeks of intravenous antimicrobials followed by possible oral suppression therapy, while the European guidelines recommend 12 weeks of orally bioavailable antibiotics.

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Section: Discussionsupporting

confidence: 89%

Prosthetic hip infection due toCampylobacter jejuni

et al. 2022

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“…A total of 13 studies were then excluded from the analysis: one reported immediate postoperative outcomes following lumbar fusion; 6 two enrolled colonoscopy cases; 26,27 three included fracture or osteoporosis cases; 2,14,28 and seven were case reports. [29][30][31][32][33][34][35] Overall, eight studies comprising 407,462 patients were included in this metaanalysis. The study selection process is shown in Figure 1.…”

Section: Resultsmentioning

confidence: 99%

Inflammatory bowel disease is associated with an increased risk of adverse events in patients undergoing joint arthroplasty

Ding

Cheng

et al. 2023

Bone Joint Res

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AimsThe present study aimed to investigate whether patients with inflammatory bowel disease (IBD) undergoing joint arthroplasty have a higher incidence of adverse outcomes than those without IBD.MethodsA comprehensive literature search was conducted to identify eligible studies reporting postoperative outcomes in IBD patients undergoing joint arthroplasty. The primary outcomes included postoperative complications, while the secondary outcomes included unplanned readmission, length of stay (LOS), joint reoperation/implant revision, and cost of care. Pooled odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using a random-effects model when heterogeneity was substantial.ResultsEight retrospective studies involving 29,738 patients with IBD were included. Compared with non-IBD controls, patients with IBD were significantly more likely to have overall complications (OR 2.11 (95% CI 1.67 to 2.66), p < 0.001), medical complications (OR 2.15 (95% CI 1.73 to 2.68), p < 0.001), surgical complications (OR 1.43 (95% CI 1.21 to 1.70), p < 0.001), and 90-day readmissions (OR 1.42 (95% CI 1.23 to 1.65), p < 0.001). The presence of IBD was positively associated with the development of venous thromboembolism (OR 1.60 (95% CI 1.30 to 1.97), p < 0.001) and postoperative infection (OR 1.95 (95% CI 1.51 to 2.51), p < 0.001). In addition, patients with IBD tended to experience longer LOS and higher costs of care.ConclusionThe findings suggest that IBD is associated with an increased risk of postoperative complications and readmission after joint arthroplasty, resulting in longer hospital stay and greater financial burden. Surgeons should inform their patients of the possibility of adverse outcomes prior to surgery and make appropriate risk adjustments to minimize potential complications.Cite this article: Bone Joint Res 2023;12(6):362–371.

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2021

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Campylobacter jejuni prosthetic joint infection in an ulcerative colitis patient in the absence of gastrointestinal symptoms

Cited by 4 publications

References 12 publications

Prosthetic hip infection due toCampylobacter jejuni

Prosthetic hip infection due toCampylobacter jejuni

Inflammatory bowel disease is associated with an increased risk of adverse events in patients undergoing joint arthroplasty

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