Camps Reaction and Related Cyclizations

Fisyuk, A. S.; Kostyuchenko, A. S.; Goncharov, D. S.

doi:10.1134/s1070428020110019

Cited by 11 publications

(1 citation statement)

References 144 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In clinical practice, 5‐amino‐[3,4′‐bipyridin]‐6(1 H )‐one 4 , known as the cardiotonic drug Amrinone, is used [17] . In addition, 3‐aminopyridin‐2(1 H )‐ones are used in the synthesis more complex biologically active compounds [18a–m] …”

Section: Introductionmentioning

confidence: 99%

Synthesis of 3‐Aminopyrido[2,1‐a]isoquinolin‐4‐one Derivatives via Condensation of Azlactones with 1‐Alkyl‐3,4‐dihydroisoquinolines

et al. 2021

View full text Add to dashboard Cite

Reactions of available 1-alkyl-3,4-dihydroisoquinolines with 4-(2,2,2-trifluoroacetyl)-, 4-acetyl-or 4-(ethoxy-methylene)-2-aryloxazol-5(4H)-ones were studied. A series of new 3-amino-6,7dihydro-4H-pyrido[2,1-a]isoquinolin-4-one derivatives was synthesized. The intermediates formed as a result of the addition of azlactone to 1-methyl-3,4-dihydroisoquinoline were isolated. The effect of the nature of the substituents, as well as the reaction conditions on the yield and structure of the title products was revealed.

show abstract

Section: Introductionmentioning

confidence: 99%

Synthesis of 3‐Aminopyrido[2,1‐a]isoquinolin‐4‐one Derivatives via Condensation of Azlactones with 1‐Alkyl‐3,4‐dihydroisoquinolines

et al. 2021

View full text Add to dashboard Cite

show abstract

Novel Approach to the Synthesis of 3-amino-4-arylpyridin-2(1H)-one Derivatives

Shuvalov

Черненко

Shatsauskas

et al. 2021

Chem Heterocycl Comp

View full text Add to dashboard Cite

The reaction of 4-arylidene-2-phenyloxazol-5(4 H )-ones with enamines of ethyl acetoacetate gave 4-aryl-2-methyl-6-oxo-5-[(phenylcarbonyl)amino]-1,4,5,6-tetrahydropyridine-3-carboxylic acid esters, which, when heated with phosphorus oxychloride, were converted into esters of 7-aryl-5-methyl-2-phenyloxazolo[5,4- b ]pyridine-6-carboxylic acids. Alkaline hydrolysis of these compounds gave 4-aryl-2-methyl-6-oxo-5-[(phenylcarbonyl)amino]-1,6-dihydropyridine-3-carboxylic acid esters. Supplementary Information The online version contains supplementary material available at 10.1007/s10593-021-02980-w.

show abstract