Camperdown hemoglobin associated with beta° thalassemia in a Brazilian child

Abstract

We report the coexistence of Hb Camperdown [b104 (G6) Arg ® Ser] and b°-thalassemia [b39 (Gln ® stop codon)] in a nine-month-old Brazilian boy. He had a relatively more severe hypochromic and microcytic anemia in comparison to his mother's b-thalassemia trait. His Hb Camperdown heterozygous father was clinically and hematologically normal. To our knowledge, this is the first description of an association of b°-thalassemia with Hb Camperdown.