“…Moreover, it is known that structural reorganization as a result of activity is required for maintenance of synaptic strength (Lamprecht and LeDoux, 2004 ; Lynch et al, 2007 ). In this regard, it has been demonstrated that CaMKII inhibition during the maintenance phase of MF-LTP prevents the activity-dependent morphological reorganization in this pathway (Juárez-Muñoz et al, 2017 ). In addition, several studies have demonstrated the interaction of CaMKII with actin polymerization (Fink et al, 2003 ; Kim et al, 2015 ), as well as with enzymes of the Rho/Rac family controlling spine dynamics, turnover and morphology (Murakoshi et al, 2011 ).…”