Camellia oil lowering blood pressure in spontaneously hypertension rats

Guo, Li‐Na; Guo, Yiting; Wu, Ping; Lü, Feng; Zhu, Junsong; Ma, Haile; Chen, Yong; Zhang, Tao

doi:10.1016/j.jff.2020.103915

Cited by 27 publications

(14 citation statements)

References 34 publications

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“…It is rich in monounsaturated fatty acids and a variety of functional active ingredients, such as squalene, phytosterols (β‐sitosterol, rapeseed sterol, and stigmasterol), polyphenols, fat‐soluble vitamins (vitamins A, B, E), and so on, which has high nutritional value and health‐care function (Shi et al., 2020). Therefore, long‐term consumption of CSO can prevent cardiovascular sclerosis, lower cholesterol, anti‐oxidation, protect liver, inhibit asthma, and so on (Chou et al., 2018; Guo et al., 2020; Lee et al., 2007, 2019; Lee & Yen, 2006).…”

Section: Introductionmentioning

confidence: 99%

Effects of different preheat treatments on volatile compounds of camellia ( Camellia oleifera Abel .) seed oil and formation mechanism of key aroma compounds

Zhou

et al. 2021

J. Food Biochem.

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Camellia oleifera (Camellia oleifera Abel.), which belongs to Theaceae, is an endemic woody edible oil tree species in China, and it is also one of the four major woody oil crops in the world (Liang et al., 2017). Camellia seed oil (CSO) is a vegetable oil extracted from camellia seeds, which fatty acid composition and physical and chemical properties are very similar to olive oil, so it is known as "Oriental Olive Oil" (Zhu et al., 2020). It is rich in monounsaturated fatty acids and a variety of functional active ingredients, such as squalene, phytosterols (β-sitosterol, rapeseed sterol, and stigmasterol), polyphenols, fat-soluble vitamins (vitamins A, B, E), and so on, which has high nutritional value and health-care function (Shi et al., 2020). Therefore, long-term consumption of CSO can prevent cardiovascular sclerosis, lower cholesterol, anti-oxidation, pro

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Section: Introductionmentioning

confidence: 99%

Effects of different preheat treatments on volatile compounds of camellia ( Camellia oleifera Abel .) seed oil and formation mechanism of key aroma compounds

Zhou

et al. 2021

J. Food Biochem.

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“…The Compendium of Materia Medica recorded that Camellia oil was tasted sweet, lubricating the intestines ( 7 ), and clearing away heat and eliminate dampness, moisturizing the lungs and eliminating phlegm. Camellia oil also has good effects on reducing swelling, relieving itching, cuts, burns, and bruises ( 8 ). In addition, it was use for the treatment of skin diseases such as dermatitis and stretch marks ( 9 ).…”

Section: Introductionmentioning

confidence: 99%

Comparison of Antioxidant and Antibacterial Activities of Camellia Oil From Hainan With Camellia Oil From Guangxi, Olive Oil, and Peanut Oil

et al. 2021

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Background/Aim: Camellia oil from Hainan (SY) is a unique vegetable oil in Hainan, China, due to the geographical environment and oil extraction only through simple physical treatments. To compare SY with camellia oil from Guangxi (SC), olive oil (GL), and peanut oil (HS), this study analyzed the antioxidant and antibacterial activity of four vegetable oils.Methods: Using Gallic acid, BHT as the control, Saccharomyces cerevisiae as the model organism, the antioxidant activities of vegetable oils were measured in vitro and in vivo, and the antibacterial activity was measured with the minimum inhibitory concentration (MIC) method.Results: The major contents of SY, SC, and HS were oleic Acid; the major content of GL was squalene. The highest total flavonoids content of SY was 39.50 ± 0.41 mg RE/g DW; and the highest total phenolic content of SC was 47.05 ± 0.72 mg GAE/g DW. SY exhibited the strongest scavenging activity of hydroxyl radical (HO·) and superoxide anions (O2-·), the IC50 value were 2.06 mg/mL, 0.62 mg/mL, respectively; and SC showed the strongest DPPH· and ABTS· scavenging activity and the reducing abilities. SY showed excellent effect on survival rate, protection rate, flavonoids uptake of S. cerevisiae cells, decreased MDA content and ROS level, inhibited CAT, POD, and GR enzyme activity. The absorption of SC total phenols was the highest by cells. The activity showed GL had a broad-spectrum antibacterial activity.Conclusion: Thus, SY shows potential antioxidant activity and provides an important reference value for people to choose edible vegetable oils.

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“…The endothelium-derived vasoconstrictor factors (EDCFs) and endothelium-derived relaxing factors (EDRFs) secreted by vascular endothelial cells can regulate blood pressure and endothelial function ( 20 ). To further explore the mechanism underlying the antihypertensive effects of DCGHs in vivo , the serum biochemical indicators of SHRs were analyzed.…”

Section: Resultsmentioning

confidence: 99%

“…The extraction of ACE and determination of its activity in the lung, kidney, heart, and artery were performed using the method described by Guo et al ( 20 ).…”

Section: Methodsmentioning

confidence: 99%

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Antihypertensive and Immunomodulatory Effects of Defatted Corn Germ Hydrolysates: An in vivo Study

Zhu

Guo

et al. 2021

Front. Nutr.

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This study investigated the antihypertensive and immunomodulatory effects of defatted corn germ hydrolysates (DCGHs) in vivo and their potential regulatory mechanisms. The systolic blood pressure (SBP) of spontaneously hypertensive rats (SHRs) was significantly reduced (10.30%) by the long-term intragastric administration of DCGHs (high doses). Also, there was drastic inhibition of angiotensin-I-converting enzyme (ACE) activity in the lung, kidney, and heart tissues by 24.53, 22.28, and 12.93%, respectively. It could regulate the blood pressure by adjusting the balance between endothelium-derived vasoconstrictor factors and endothelium-derived relaxing factors. Meanwhile, DCGHs enhanced the phagocytosis of mononuclear macrophages, cellular immunity, and humoral immunity of ICR mice by increasing the phagocytic index of mononuclear macrophages (23.71%), ear swelling degree (44.82%), and antibody levels (52.32%). Moreover, it stimulated the release of immunoactive substances (e.g., lysozyme, interferon-γ, immunoglobulin G, and complement 3). Consequently, DCGHs could suitably be used in the formulation of novel functional foods with antihypertensive and immunomodulatory properties.

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Camellia oil lowering blood pressure in spontaneously hypertension rats

Cited by 27 publications

References 34 publications

Effects of different preheat treatments on volatile compounds of camellia ( Camellia oleifera Abel .) seed oil and formation mechanism of key aroma compounds

Effects of different preheat treatments on volatile compounds of camellia ( Camellia oleifera Abel .) seed oil and formation mechanism of key aroma compounds

Comparison of Antioxidant and Antibacterial Activities of Camellia Oil From Hainan With Camellia Oil From Guangxi, Olive Oil, and Peanut Oil

Antihypertensive and Immunomodulatory Effects of Defatted Corn Germ Hydrolysates: An in vivo Study

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