Calorimetric investigations of the different castes of honey bees, Apis mellifera carnica

Fahrenholz, L.; Lamprecht, I.; Schricker, B.

doi:10.1007/bf00398337

Cited by 40 publications

(21 citation statements)

References 53 publications

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“…Enhanced antioxidant defenses in queens are not a likely explanation, as one study has shown queen ants have a reduced expression of Cu/Zn-SOD compared with shorter-living workers (282) while others have shown that queen honeybees generally have the same (or, in some cases, lower) levels of antioxidant defenses than worker honeybees (68,370). The massspecific metabolic rates of worker and queen honeybees are essentially the same (96). Recent measurements show that queen and worker honeybees have different membrane fatty acid composition and that the peroxidation index of phospholipids of from queen honeybees is ϳ33% of that of workers (122).…”

Section: Ectothermic Vertebrates and Invertebratesmentioning

confidence: 99%

Life and Death: Metabolic Rate, Membrane Composition, and Life Span of Animals

Hulbert¹,

Pamplona²,

Buffenstein

et al. 2007

Physiological Reviews

740

725

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Maximum life span differences among animal species exceed life span variation achieved by experimental manipulation by orders of magnitude. The differences in the characteristic maximum life span of species was initially proposed to be due to variation in mass-specific rate of metabolism. This is called the rate-of-living theory of aging and lies at the base of the oxidative-stress theory of aging, currently the most generally accepted explanation of aging. However, the rate-of-living theory of aging while helpful is not completely adequate in explaining the maximum life span. Recently, it has been discovered that the fatty acid composition of cell membranes varies systematically between species, and this underlies the variation in their metabolic rate. When combined with the fact that 1) the products of lipid peroxidation are powerful reactive molecular species, and 2) that fatty acids differ dramatically in their susceptibility to peroxidation, membrane fatty acid composition provides a mechanistic explanation of the variation in maximum life span among animal species. When the connection between metabolic rate and life span was first proposed a century ago, it was not known that membrane composition varies between species. Many of the exceptions to the rate-of-living theory appear explicable when the particular membrane fatty acid composition is considered for each case. Here we review the links between metabolic rate and maximum life span of mammals and birds as well as the linking role of membrane fatty acid composition in determining the maximum life span. The more limited information for ectothermic animals and treatments that extend life span (e.g., caloric restriction) are also reviewed.

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Section: Ectothermic Vertebrates and Invertebratesmentioning

confidence: 99%

Life and Death: Metabolic Rate, Membrane Composition, and Life Span of Animals

Hulbert¹,

Pamplona²,

Buffenstein

et al. 2007

Physiological Reviews

740

725

View full text Add to dashboard Cite

show abstract

“…Previous studies have dismissed purely mechanistic or stochastic explanations of ageing and longevity in eusocial insects in favour of evolutionary ones (Keller & Genoud 1997). These studies apparently overlook the metabolic implications of potentially large differentials in physical activity level between relatively sedentary queens and working castes involved in foraging, guarding and nest maintenance (Fahrenholz et al 1992;Yan & Sohal 2000). On the other hand, our results for locusts suggest that both evolutionary and stochastic mechanisms are applicable to insect ageing and longevity.…”

Section: Discussion (A) Strong Correlation Of Neurolipofuscin Concentmentioning

confidence: 59%

Death rates reflect accumulating brain damage in arthropods

et al. 2005

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We present the results of the first quantitative, whole-lifespan study of the relationship between age-specific neurolipofuscin concentration and natural mortality rate in any organism. In a convenient laboratory animal, the African migratory locust, Locusta migratoria, we find an unusual delayed-onset neurolipofuscin accumulation pattern that is highly correlated with exponentially accelerating age-specific GompertzMakeham death rates in both males (rZ0.93, pZ0.0064) and females (rZ0.97, pZ0.0052). We then test the conservation of this association by aggregating the locust results with available population-specific data for a range of other terrestrial, freshwater, marine, tropical and temperate arthropods whose longevities span three orders of magnitude. This synthesis shows that the strong association between neurolipofuscin deposition and natural mortality is a phylogenetically and environmentally widespread phenomenon (rZ0.96, p!0.0001). These results highlight neurolipofuscin as a unique and outstanding integral biomarker of ageing. They also offer compelling evidence for the proposal that, in vital organs like the brain, either the accumulation of toxic garbage in the form of lipofuscin itself, or the particular molecular reactions underlying lipofuscinogenesis, including free-radical damage, are the primary events in senescence.

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“…In addition, the faster queen development is fuelled by higher mitochondrial activity [42], which may provide a cellular mechanism for the longevity of queens: In the light of similar mass-specific metabolic rates [43], more mitochondria may make queens less susceptible to the toxic by-products of the oxidative phosphorylation pathway because a higher mitochondrial redundancy reduces oxidative stress and makes cells more resistant to it. This reduced stress hypothesis is compatible with findings that the upregulation of classic antioxidant defence genes seems not to be responsible for the increased life expectancy of honey bee queens [44].…”

Section: Physiological Regulation Of Longevitymentioning

confidence: 99%

Ties between ageing plasticity and reproductive physiology in honey bees (Apis mellifera) reveal a positive relation between fecundity and longevity as consequence of advanced social evolution

Rueppell

Aumer

Moritz

2016

Current Opinion in Insect Science

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Honey bees (Apis mellifera) are the best studied model of aging among the social insects. As in other social insects, the reproductive queen far outlives her non-reproductive workers despite developing from the same genome in the same colony environment. Thus, the different social roles of the two female castes are critical for the profound phenotypic plasticity. In several special cases, such as the reproductive workers of Apis mellifera capensis, within-caste plasticity enables further studies of the fecundity – longevity syndrome in honey bees. At present, molecular evidence suggests that a reorganization of physiological control pathways may facilitate longevity of reproductive individuals. However, the social role and social environment of the different colony members are also very important and one of the key future questions is how much social facilitation versus internal regulation is responsible for the positive association between fecundity and longevity in honey bees.

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Calorimetric investigations of the different castes of honey bees, Apis mellifera carnica

Cited by 40 publications

References 53 publications

Life and Death: Metabolic Rate, Membrane Composition, and Life Span of Animals

Life and Death: Metabolic Rate, Membrane Composition, and Life Span of Animals

Death rates reflect accumulating brain damage in arthropods

Ties between ageing plasticity and reproductive physiology in honey bees (Apis mellifera) reveal a positive relation between fecundity and longevity as consequence of advanced social evolution

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