Callus conclusion

Dainty, A.L.; Goulding, K. H.; Robinson, Peter; Simpkins, I.; Trevan, M. D.

doi:10.1016/0167-7799(85)90010-1

Cited by 1 publication

(1 citation statement)

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“…3. with the d.c. magrtetic field component hulled, viscous damping in biological systems: such ions are unlikely to experience cyclotron motion in situ [7,[12][13][14]. Some of these issues may be eliminated or minimized if special circumstances are invoked such as restricting a.e./d.c, field interactions to the interior of membrane channels [15], where water may be stripped • from ions, or by restricting interaction sites to the cell surface where hydrophobic pockets may exist that strip the hydration shell from ions [5].…”

Section: Discussionmentioning

confidence: 99%

Time‐varying and static magnetic fields act in combination to alter calcium signal transduction in the lymphocyte

1992

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We have tested the hypothesis that extremely low frequency (ELF) time.varying magnetic fields act in combination with static magnetic fields to alter calcium ~ignalling in the lymphocyte. Results indicate that a 60-rain exposure of thymic lymphocytes at 37 ± 0.05°C to a 16 Hz, 421 mG (42.1 /aT) magnetic field simultaneously with a colinear static magnetic field of 234 mG (23.4/aT) (a.c./d.c. field intensity ratio = 1.8) inhibits calcium influx triggered by the mitogen Concanavalin A. Significantly, resting lymphocytes do not respond to the fields, thus, only mitogen-activated cells underBoin~ calcium signalling exhibit a field response. These results indicate that signal transduction involving calcium is an important biological cottslrclbtt which operates to mediate this field interaction. Additional split field exposures show that the presence of the a.c. field or the d.c. field alone does not produce an effect. This is consistent with a proposed parametric resonance theory of interaction of low intensity magnetic fields with biological systems (L.L. Ledncv (1991) Bioelextromagnetics 12, 71-75), whlch predicts the oceurran~ of biological effects at Sl~cific values for the frequency and field intensity of the ELF and static magnetic fields.

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Section: Discussionmentioning

confidence: 99%