Call-Fleming syndrome associated with convexity subarachnoid hemorrhage

Robert, Thomas; Oumarou, Gaston; Villard, J∘; Marcini, A. Kawkabani; Daniel, Roy Thomas; Levivier, Marc; Uské, A

doi:10.1016/j.clineuro.2012.07.029

Cited by 2 publications

(3 citation statements)

References 9 publications

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“…A great variety of differential diagnoses must be investigated simultaneously, as infectious arteritis, and inflammatory brain vasculitis, such as giant cell arteritis and polyarteritis nodosa 1,2,10 .…”

Section: Introduction Cases Presentationmentioning

confidence: 99%

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Reversible Cerebral vasoconstriction syndrome associated with the use of sibutramine

Silva¹,

Demore²,

Reis³

et al. 2021

jbnc

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The reversible cerebral vasoconstriction syndrome, also known as Call-Fleming syndrome, was initially described in 1988, and is characterized by a clinical syndrome of headaches episodes, generally the “thunderclap” pattern, due to a deregulation of the vascular tonus, leading to segmentary cerebral vasoconstriction and secondary neurological deficits, including those by ischemic or hemorrhagic stroke. In this paper, we present two illustrative cases of this syndrome due to the use of sibutramine. To our knowledge, this situation hasn’t been described as related drug before.

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Section: Introduction Cases Presentationmentioning

confidence: 99%

“…Regarding the management, some authors suggest that RCVS justifies both vasospasm monitorization with transcranial Doppler and calcium/magnesium channel blockers 2 .…”

Section: Introduction Cases Presentationmentioning

confidence: 99%

Reversible Cerebral vasoconstriction syndrome associated with the use of sibutramine

Silva¹,

Demore²,

Reis³

et al. 2021

jbnc

View full text Add to dashboard Cite

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“…e most common clinical feature of RCVS is a severe acute headache, which is often referred to as a thunderclap headache due to the nature of its presentation. [5] RCVS has been reported in association with ischemic stroke and convexity subarachnoid hemorrhage (SAH); [9] however, few reports have described RCVS concomitant with cerebral venous sinus thrombosis (CVST). is is the first case report that describes RCVS concomitant with CVST in a woman who underwent ovarian tumor resection and was followed-up with singlephoton emission computed tomography (SPECT) and 3.0 T magnetic resonance imaging (MRI).…”

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confidence: 99%

Reversible cerebral vasoconstriction syndrome concomitant with cerebral venous sinus thrombosis following ovarian tumor resection: A report of two cases

Shimizu¹,

Tsuchiya

Fujisawa

2020

Surgical Neurology International

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Background: Reversible cerebral vasoconstriction syndrome (RCVS) presents with characteristic clinical, brain imaging, and angiographic findings. The most common clinical feature of RCVS is a severe acute headache, which is often referred to as a thunderclap headache due to the nature of its presentation. It may occur spontaneously or may be provoked by various precipitating factors. We present a rare case of RCVS concomitant with cerebral venous sinus thrombosis (CVST) in a woman who underwent resection of an ovarian tumor. Case Description: Case 1 – A 42-year-old woman was admitted to our hospital with severe headache radiating to the neck, with associated vomiting. She revealed a medical history of ovarian cancer and underwent an operation for the resection of the tumor, a month before presentation. After resection, her estradiol (E2) levels were reduced from 288 pg/ml to 31 pg/ml (normal range, 0–49 pg/ml). Initial imaging on admission to our hospital revealed the left posterior convexity subarachnoid hemorrhage. Magnetic resonance angiography (MRA) showed findings consistent with RCVS affecting the left posterior cerebral artery. Magnetic resonance venography (MRV) showed CVST of the left transverse and sigmoid sinuses. Single-photon emission computed tomography (SPECT) showed a left posterior ischemic lesion. These findings improved following treatment with nimodipine and anticoagulant. Case 2 – A 39-year-old woman presented with holocranial headache associated with vomiting. She was diagnosed with an ovarian tumor. She underwent an operation 3 months before presentation. After tumor resection, her E2 level decrease from 193 pg/ml to 19 pg/ml (normal range, 0–49 pg/ml). Magnetic resonance angiography (MRA) confirmed the presence of a vasospasm involving the right anterior cerebral artery. Magnetic resonance venography (MRV) confirmed the presence of thrombosis involving the superior sagittal sinus. She was discharged on postpartum day 31 without neurological deficits after treatment with anticoagulants. At her 3-month follow-up, both MRA and MRV were within the normal limits. Conclusion: This is the first report of two women diagnosed with RCVS with concomitant CVST following ovarian tumor resection. Marked reductions in postoperative E2 levels could have contributed to the development of CVST and RCVS.

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Call-Fleming syndrome associated with convexity subarachnoid hemorrhage

Cited by 2 publications

References 9 publications

Reversible Cerebral vasoconstriction syndrome associated with the use of sibutramine

Reversible Cerebral vasoconstriction syndrome associated with the use of sibutramine

Reversible cerebral vasoconstriction syndrome concomitant with cerebral venous sinus thrombosis following ovarian tumor resection: A report of two cases

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