Calixarene‐Guest Complexes: The Next Innovation in Delivery of Drugs and Biologics
Sheetal Muley,
Hozefa Dhila,
Meghana Gote
Abstract:Calixarenes are third generation of macrocyclic molecules with excellent biocompatibility currently being researched extensively for their diverse potential as therapeutic candidates and for delivery of drugs and biologics. This review discusses the unique structural features which allow them to selectively bind to a wide variety of guest molecules within their hydrophobic cavity, as well as complex with other molecules on their upper and lower rims to enable their application for encapsulation of drugs for ta… Show more
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