Calix[4]resorcinolarene with (thiophosphoryl)thiomethyl fragments on the lower rim of the molecule

New calix[4]resorcinols containing aldehyde fragments in the molecule

“…In the recent years, functionalized calix [4]resorcinols attract wide attention of researches since they are of undoubted interest as complex forming agents, metal extragents, stabilizers of polymers. 1,2 So far, two general approaches to the synthesis of calixarene derivatives have been developed.…”

“…Calix [4]resorcinols having aminomethyl fragments in the aromatic rings at ortho position to the hydroxy groups are of undoubted interest as a spatially organized matrix. The first representative of this class of compounds was obtained by the Mannich reaction of calix [4]resorcinol, formaldehyde, and a sec ondary amine. 5 Recently, we have obtained the Mannich bases containing acetal groups by the reaction of calix [4] resorcinols with methylaminoacetaldehyde dimethyl acetal in the presence of formaldehyde.…”

“…The first representative of this class of compounds was obtained by the Mannich reaction of calix [4]resorcinol, formaldehyde, and a sec ondary amine. 5 Recently, we have obtained the Mannich bases containing acetal groups by the reaction of calix [4] resorcinols with methylaminoacetaldehyde dimethyl acetal in the presence of formaldehyde. 6,7 It should be noted that according to the literature data, modifications of calix [4]resorcinols by the Mannich reaction, as a rule, lead to the tetra substituted products irrespective of the ratio of reagents.…”

“…3 In a number of cases, acetal deriva tives can be successfully used instead of aldehydes. 4 The second approach is based on the functionalization of prepared calixarene matrix with participation of hydroxy groups or the aromatic ring. Calix [4]resorcinols having aminomethyl fragments in the aromatic rings at ortho position to the hydroxy groups are of undoubted interest as a spatially organized matrix.…”

“…4 The second approach is based on the functionalization of prepared calixarene matrix with participation of hydroxy groups or the aromatic ring. Calix [4]resorcinols having aminomethyl fragments in the aromatic rings at ortho position to the hydroxy groups are of undoubted interest as a spatially organized matrix. The first representative of this class of compounds was obtained by the Mannich reaction of calix [4]resorcinol, formaldehyde, and a sec ondary amine.…”