The persistence or recurrence of symptoms after antireflux surgery is associated with poor study and initial approach, failures in surgical technique and risk factors specific to the patient. In order to describe the symptoms that lead to a new intervention, time since the first procedure, the technique used and the characteristics of the patients, a retrospective systematic review of 100 clinical records of cases undergoing reintervention of antirreflux surgery during the last four years was carried out in Angeles Pedregal Hospital in Mexico City. Cases with up to three previous surgeries were found, the results showed that heartburn (65%), regurgitation (58%) and epigastric pain (28%) were the most frequent symptoms. The most important isolated risk factor was obesity (23%). More than 50% underwent reoperation within the first 10 years, with slippage of the fundoplication being the most common failure mechanism (71%). Although the results largely coincide with the literature, the systematic comparison of cases with two or more surgeries as in our sample has been reported in few studies in the laparoscopic era, so the present work contributes to the analysis of cases with multiple anti-reflux surgical treatments.