Abstract:Optical tweezers are an important tool in biophysics for their ability to noninvasively control microscopic particles, and measure forces in cellular environments. The trap must be calibrated for there to be a quantified force measurement. In this thesis, I use simulation to investigate the forces in optical tweezers and calibration of these forces.There are many methods which can be used to calibrate the forces. I first discuss the use of escape force calibration in detail. Using a combination of dynamic simu… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.