Calibration of instrument and sample parameters for small angle X-ray scattering

Wei, Yanru; Li, Zhi Hong

doi:10.1080/10739149.2016.1143838

Cited by 11 publications

(3 citation statements)

References 10 publications

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“…SAXS patterns were measured at Beamline 1W2A at the Beijing Synchrotron Radiation Facility [ 22 ]. The powder samples were supported on adhesive tape for measurement, which was used for background correction for the samples [ 23 ]. The sample-to-detector distance for SAXS was 1.58 m, calibrated with the diffraction ring of a standard sample.…”

Section: Methodsmentioning

confidence: 99%

Dispersion Performances and Fluorescent Behaviors of Naphthalic Anhydride Doped in Poly(acrylic acid) Frameworks for pH-Sensitive Ibuprofen Delivery via Fractal Evolution

Cui

Wang

et al. 2023

Polymers

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The pH-responsive fluorescent P(1,8-naphthalic anhydride (NA)-acrylic acid (AA)) matrix was successfully prepared by a doping method using poly(acrylic acid) (PAA) as a pH-sensitive polymer and NA as a fluorescent tracer. The fluorescent behaviors of the used NA dispersed in PAA frameworks were demonstrated based on fractal features combined with various characterizations, such as small-angle X-ray scattering (SAXS) patterns, photoluminescence (PL) spectra, scanning electron microscope (SEM) images, thermogravimetry (TG) profiles, Fourier transform infrared (FT-IR) spectroscopy, and time-resolved decays. The effects of NA-doping on the representative fluorescent P(NA-AA) were investigated, in which the fluorescent performance of the doped NA was emphasized. The results indicated that aggregated clusters of the doped NA were gradually serious with an increase in NA doping amount or extension of NA doping time, accompanied by an increase in mass fractal dimension (Dm) values. Meanwhile, the doped NA presented stable fluorescent properties during the swelling–shrinking process of PAA. Ibuprofen (IBU) was used as a model drug, and fractal evolutions of the obtained P(NA-AA) along with the drug loading and releasing behaviors were evaluated via SAXS patterns, in which the drug-loaded P(NA-AA) presented surface fractal (Ds) characteristics, while the Dm value varied from 2.94 to 2.58 during sustained drug-release in pH 2.0, indicating occurrences of its structural transformation from dense to loose with extension of IBU-releasing time. Finally, the cytotoxicity and cellular uptake behaviors of the obtained P(NA-AA) were preliminarily explored. These demonstrations revealed that the resultant P(NA-AA) should be a potential intelligent-responsive drug carrier for targeted delivery.

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Section: Methodsmentioning

confidence: 99%

Dispersion Performances and Fluorescent Behaviors of Naphthalic Anhydride Doped in Poly(acrylic acid) Frameworks for pH-Sensitive Ibuprofen Delivery via Fractal Evolution

Cui

Wang

et al. 2023

Polymers

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“…A Linkam thermal stage (Linkam Scientific Instruments, U.K.) was used for temperature control (±0.1 °C). The program Fit2D was used to convert the 2D scattering data to 1D profiles, and the dead data collected by the Pilatus 1MF detector were recovered using a program developed by Zhihong Li. , …”

Section: Methodsmentioning

confidence: 99%

“…The program Fit2D was used to convert the 2D scattering data to 1D profiles, and the dead data collected by the Pilatus 1MF detector were recovered using a program developed by Zhihong Li. 49,50 2.4. Differential Scanning Calorimetry.…”

Section: Introductionmentioning

confidence: 99%

Effect of Imidazolium-Based Ionic Liquids on the Structure and Phase Behavior of Palmitoyl-oleoyl-phosphatidylethanolamine

et al. 2019

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Among various applications, ionic liquids (ILs) have been used as antimicrobial agents in laboratories, possibly through induction of the leakage of bacteria. A molecular-level understanding of the mechanism that describes how ILs enhance the permeation of membranes is still lacking. In this study, the effects of imidazolium-based ILs with different alky chain lengths on the structure and phase behavior of 1-palmitoyl-2-oleoyl-phosphatidylethanolamine (POPE), which is a representative bacteria-membrane-rich lipid, have been investigated. By employing differential scanning calorimetry and synchrotron small-and wide-angle X-ray scattering techniques, we found that ILs with longer alkyl chains influenced the phase behavior more effectively, and lower IL concentrations are needed to induce phase separation for both lamellar liquid crystalline phase and nonlamellar inverted hexagonal phase of POPE. Interestingly, the IL with an alkyl chain of 12 carbon atoms ([C 12 mim]Cl) shows a difference. It exhibits a stronger disturbing effect on the POPE bilayer structure than [C 16 mim]Cl, indicating that the ability of ILs to influence the membrane structures is dependent not only on the alkyl chain length of ILs, but also on the degree of matching of the alkyl chain lengths of ILs and lipids. The new lamellar and nonlamellar structures induced by ILs both have smaller repeat distances than that of pure POPE, implying thinner membrane structures. Data of the fluorescence-based vesicle dye leakage assay are consistent with these results, particularly the defects caused by IL-induced phase separation can enhance the membrane permeability markedly. The present work may shed light on our understanding of the antimicrobial mechanism of ILs.

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A Review on Friction Stir Processing of Titanium Alloy: Characterization, Method, Microstructure, Properties

Ding

Fan

Wang

2019

Metall Mater Trans B

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Calibration of instrument and sample parameters for small angle X-ray scattering

Cited by 11 publications

References 10 publications

Dispersion Performances and Fluorescent Behaviors of Naphthalic Anhydride Doped in Poly(acrylic acid) Frameworks for pH-Sensitive Ibuprofen Delivery via Fractal Evolution

Dispersion Performances and Fluorescent Behaviors of Naphthalic Anhydride Doped in Poly(acrylic acid) Frameworks for pH-Sensitive Ibuprofen Delivery via Fractal Evolution

Effect of Imidazolium-Based Ionic Liquids on the Structure and Phase Behavior of Palmitoyl-oleoyl-phosphatidylethanolamine

A Review on Friction Stir Processing of Titanium Alloy: Characterization, Method, Microstructure, Properties

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