Calibration of an eye oximeter with a dynamic eye phantom

Nabili, A.; Bardakci, D.; Helling, K.; Matyas, Cynthia E.; Muro, Shigeo; Ramella‐Roman, Jessica C.

doi:10.1117/12.767556

Cited by 2 publications

(3 citation statements)

References 8 publications

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“…It is also important to note that this is a largely simplified model of a human eye since it does not consider the choroid and the RPE effect whose impact on the total remitted spectrum will be clarified in section 3. A study that includes this layers in underway [22].…”

Section: In Vitro Testingmentioning

confidence: 99%

Measurement of oxygen saturation in the retina with a spectroscopic sensitive multi aperture camera

Ramella‐Roman¹,

Mathews²,

Kandimalla³

et al. 2008

Opt. Express

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We introduce a new multi aperture system capable of capturing six identical images of the human fundus at six different spectral bands. The system is based on a lenslet array architecture and is well suited for spectroscopy application. The multi-aperture system was interfaced with a fundus camera to acquire spectroscopic sensitive images of the retina vessel and ultimately to calculate oxygen saturation in the retina in vivo. In vitro testing showed that the system is able to accurately reconstruct curves of partially oxygenated hemoglobin. In vivo testing on healthy volunteers was conducted and yielded results of oxygen saturation similar to the one reported in the literature, with arterial SO(2) approximately 0.95 and venous SO(2) approximately 0.5.

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Section: In Vitro Testingmentioning

confidence: 99%

Measurement of oxygen saturation in the retina with a spectroscopic sensitive multi aperture camera

Ramella‐Roman¹,

Mathews²,

Kandimalla³

et al. 2008

Opt. Express

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show abstract

“…The corresponding pseudo-colored fun map is displayed in Figure 2. In recent decades, researchers have made great efforts in the area al-wavelength retinal oximetry to improve its repeatability [18][19][20][21], sensitivity [ bration [23][24][25][26][27][28], etc. These studies are helpful for the clinical application and pr of retinal oximetry.…”

Section: Introductionmentioning

confidence: 99%

“…Vessel segmentation is a significant step in the SO 2 calcula vessels. Although many retinal vessel segmentation algorithms have bee the literature [34][35][36][37][38][39][40][41][42], they cannot be directly applied to spectrophoto In recent decades, researchers have made great efforts in the area of dual-wavelength retinal oximetry to improve its repeatability [18][19][20][21], sensitivity [22], calibration [23][24][25][26][27][28], etc. These studies are helpful for the clinical application and promotion of retinal oximetry.…”

Section: Introductionmentioning

confidence: 99%

A Novel Hybrid Retinal Blood Vessel Segmentation Algorithm for Enlarging the Measuring Range of Dual-Wavelength Retinal Oximetry

et al. 2023

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The non-invasive measurement of hemoglobin oxygen saturation (SO2) in retinal vessels is based on spectrophotometry and the absorption spectral characteristics of the tissue. The dual-wavelength retinal images are simultaneously captured via retinal oximetry. SO2 is calculated by processing a series of images and by calculating the optic density ratio of two images. However, existing SO2 research is focused on the thick vessels in the high-clarity region of retinal images. However, the thin vessels in the low-clarity region could provide significant information for the detection and diagnosis of neovascular diseases. To this end, we proposed a novel hybrid vessel segmentation algorithm. Firstly, a median filter was employed for image denoising. Secondly, high- and low-clarity region segmentation was carried out based on a clarity histogram. The vessels in the high-clarity areas were segmented after implementing a Gaussian filter, a matched filter, and morphological segmentation. Additionally, the vessels in the low-clarity areas were segmented using a guided filter, matched filtering, and dynamic threshold segmentation. Finally, the results were obtained through image merger and morphological operations. The experimental results and analysis show that the proposed method can effectively segment thick and thin vessels and can extend the measuring range of dual-wavelength retinal oximetry.

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Calibration of an eye oximeter with a dynamic eye phantom

Cited by 2 publications

References 8 publications

Measurement of oxygen saturation in the retina with a spectroscopic sensitive multi aperture camera

Measurement of oxygen saturation in the retina with a spectroscopic sensitive multi aperture camera

A Novel Hybrid Retinal Blood Vessel Segmentation Algorithm for Enlarging the Measuring Range of Dual-Wavelength Retinal Oximetry

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