Caliber-Persistent Artery

Abstract

Caliber-persistent artery (CPLA) of the lip is a common vascular anomaly in which a main arterial branch extends to the surface of the mucous tissue with no reduction in its diameter. It usually manifests as pulsatile papule, is easily misdiagnosed, and is observed more frequently among older people, suggesting that its development may involve a degenerative process associated with aging; CPLA is also characterized by the loss of tone of the adjacent supporting connective tissue. Although the diagnosis is clinical, high-resolution Doppler ultrasound is a useful noninvasive tool for evaluating the lesion. This report describes the case of a 58-year-old male patient who complained of a lesion of the lower lip with bleeding and recurrent ulceration. The patient was successfully treated in our hospital after a diagnosis of CPLA and is currently undergoing a clinical outpatient follow-up with no complaints.

Calibre persistent artery of the nape

“…Added risk factors are nonsteroidal anti-inflammatory drugs, alcohol, actinic damage, arterial hypertension, cardiovascular disease, renal failure or diabetes. 1,8 However, other cases have been described in the literature that, like ours, occurred in young patients without comorbidities, which calls into question the previous hypothesis. Kocyigit 7 proposed that CPA is a sporadic, non-family congenital malformation, undiagnosed until it becomes symptomatic.…”

Caliber-persistent labial artery: report of 3 cases

“…It occurs more frequently with aging, suggesting that a degenerative process of the vascular wall may be involved. 2 …”

Caliber Persistent Artery in the Upper Lip: A Case Report with Unusual Histopathological Findings

“…(8,11). Histologically, CPLA lesions are characterized by a normal muscular artery with irregular light and unusual size for a submucosal location (1). Vascular alteration fragments were observed during the histopathological examination of the present case, with a thick artery presenting stenotic light, where it was possible to observe the tunica intima layers (coated by endothelial cells and supported by loose subendothelial connective tissue), the internal elastic limit (formed by elastic fibers), the middle tunica (formed by concentric layers of smooth muscle cells) and, more externally, the adventitial tunica composed of loosely arranged collagen fibers.…”

“…Subsequently, Miko et al (4) renamed it as a "caliber" persistent labial artery, as it is known today. The caliber persistent labial artery has also been described in gastrointestinal tract sites, such as the stomach and jejunum (1). However, this condition is more common in the lower (about 80% of lesions) and upper lips, and may also appear on the palate (2,(5)(6)(7).…”

“…Caliber persistent labial artery (CPLA) consists in a dilated portion of the main branch of the labial artery that penetrates the submucosal tissue without loss of caliber (1,2). Howell and Freeman (3) initially named the condition in 1973 as a "prominent inferior labial artery".…”