Caliber of Intracranial Arteries as a Marker for Cerebral Small Vessel Disease

Chen, Zhaoyao; Li, Hui; Wu, Minghua; Chang, Cheng; Fan, Xin; Liu, Xinfeng; Xu, Gelin

doi:10.3389/fneur.2020.558858

Cited by 8 publications

(5 citation statements)

References 23 publications

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“…In the study that did not report parent artery diameter, mean diameter of the parent artery reported by other sources was used as a proxy. All reported aneurysms in this study were in arteries whose mean diameter + standard deviation was less than 3.5 mm, 7 including the ACA, 15 the ACoA, 16 the MCA, 17 and the PCA. 18…”

Section: Resultsmentioning

confidence: 73%

Patient outcomes after treatment of brain aneurysm in small diameter vessels with the silk vista baby flow diverter: A systematic review

et al. 2022

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Background The Silk Vista Baby (SVB, BALT) is a first-in-class flow-diverter device delivered using a 0.017” microcatheter, designed for the treatment of intracranial aneurysms, including those in small diameter vessels. This study reports a systematic literature review (SLR) to evaluate the safety and efficacy of using SVB to treat intracranial aneurysms in vessels less than 3.5 mm in diameter. Methods We performed a PRISMA-compliant SLR to evaluate the outcomes of SVB in the treatment of aneurysms in small intracranial vessels. Primary outcomes were occlusion status and major stroke, and secondary outcomes included all-cause mortality, procedure-related neurologic death, and post-operative aneurysm rupture. Data were expressed as descriptive statistics only. Results A total of four studies, including 163 patients with 173 intracranial aneurysms, were included. The most common aneurysm locations were the anterior cerebral artery (24.9% [43/173]), the middle cerebral artery (24.3% [42/173]), and the anterior communicating artery (23.1% [40/173]). Parent artery diameter ranged from 0.9 mm to 3.6 mm, and 29% were acutely or previously ruptured aneurysms. Overall, complete or near-complete occlusion was 72.1% on early-term follow-up. Mortality rate among the studies was 2.5%, with 3 instances adjudicated as neurologic deaths (1.8%). Major stroke was noted in 1.2% of cases, and branch occlusion or stent thrombus formation in 5.5%. Conclusion Our review suggests that SVB is a safe and effective treatment for intracranial aneurysms in small vessels. Further prospective and comparative studies with patient outcome data specific to aneurysm location are needed to confirm the safety and efficacy of SVB.

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Section: Resultsmentioning

confidence: 73%

Patient outcomes after treatment of brain aneurysm in small diameter vessels with the silk vista baby flow diverter: A systematic review

et al. 2022

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“…High-resolution IVIM estimates from voxels mainly occupied by vessels, such as small arterials with relatively high blood flow [ 33 , 34 ], may yield high

and

estimates. Consequently, this could potentially result in categorizing them as outliers.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Whole Brain Intravoxel Incoherent Motion (IVIM) Imaging

Lipiński,

Bogorodzki

2024

Diagnostics

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Intravoxel Incoherent Motion (IVIM) imaging provides non-invasive perfusion measurements, eliminating the need for contrast agents. This work explores the feasibility of IVIM imaging in whole brain perfusion studies, where an isotropic 1 mm voxel is widely accepted as a standard. This study follows the validity of a time-limited, precise, segmentation-ready whole-brain IVIM protocol suitable for clinical reality. To assess the influence of SNR on the estimation of S0, f, D*, and D IVIM parameters, a series of measurements and simulations were performed in MATLAB for the following three estimation techniques: segmented grid search, segmented curve fitting, and one-step curve fitting, utilizing known “ground truth” and noised data. Scanner-specific SNR was estimated based on a healthy subject IVIM MRI study in a 3T scanner. Measurements were conducted for 25.6 × 25.6 × 14.4 cm FOV with a 256 × 256 in-plane resolution and 72 slices, resulting in 1 × 1 × 2 mm voxel size. Simulations were performed for 36 SNR levels around the measured SNR value. For a single voxel grid, the search algorithm mean relative error Ŝ0, f^, D^*, and D^ of at the expected SNR level were 5.00%, 81.91%, 76.31%, and 18.34%, respectively. Analysis has shown that high-resolution IVIM imaging is possible, although there is significant variation in both accuracy and precision, depending on SNR and the chosen estimation method.

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“…High-resolution IVIM estimates from voxels mainly occupied by vessels, such as small arterials with relatively high blood flow [33,34], may yield high 𝑓 and 𝐷 * estimates. Consequently, this could potentially result in categorizing them as outliers.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of Whole Brain Intra Voxel Incoherent Motion (IVIM) Imaging

Lipiński,

Bogorodzki

2024

Preprint

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Intra Voxel Incoherent Motion (IVIM) imaging provides non-invasive perfusion measurements, eliminating the need for contrast agents. The aim of this work was to explore the feasibility of IVIM in whole brain perfusion studies, where isotropic 1mm voxel is widely accepted as a standard. This study treats on validity of time limited, precise, segmentation ready Whole Brain IVIM imaging protocol suitable for clinical reality. To assess the influence of SNR on the estimation of S0, f, D* and D IVIM parameters a series of measurements and simulations under MATLAB environment were performed for three estimation techniques, utilizing known “ground truth” and noised data. Scanner specific SNR was estimated based on healthy subject IVIM MRI study in 3T scanner. Measurements were conducted for 25,6x25,6x14,4 cm FOV with 256x256 in plane resolution and 72 slices resulting in 1x1x2 mm voxel size. Simulations were performed for 36 SNR levels around measured SNR value. Single voxel grid search estimation method mean relative error for S0 f D* D estimates at measured SNR level were: 5.00%,81.91%, 76.31%, 18.34% respectively. Analysis has shown that high resolution IVIM is possible, although there is significant variation in estimation accuracy and precision depending on SNR level and chosen estimation method.

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Caliber of Intracranial Arteries as a Marker for Cerebral Small Vessel Disease

Cited by 8 publications

References 23 publications

Patient outcomes after treatment of brain aneurysm in small diameter vessels with the silk vista baby flow diverter: A systematic review

Patient outcomes after treatment of brain aneurysm in small diameter vessels with the silk vista baby flow diverter: A systematic review

Evaluation of Whole Brain Intravoxel Incoherent Motion (IVIM) Imaging

Evaluation of Whole Brain Intra Voxel Incoherent Motion (IVIM) Imaging

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