Calenduloside a fromCalendula officinalis

Abstract

];'he epigeal part of Calendula officinalis has been studied previously [1,2]. We have investigated the roots of this plant collected in September 196q by P. N. KibaI'chich in the Moscow region. By the usual method for isolating triterpene glycosides [8], we obtained a mixture of substances consisting, according to thin-layer chromatography, of eight glycosides which we named, in increasing order of polarity, calendulosides

Phytochemical Constituents and Pharmacological Activities of Calendula officinalis Linn (Asteraceae): A Review

“…Various terpenoids (Table 2) have been reported from the petroleum ether extract of C.officinalis flowers. They include sitosterols, stigmasterols [9], diesters of diols [10], 3monoesters of taraxasterol, ψ-taraxasterol, lupeol [11,12], erythrodiol, brein [13,14], ursadiol [15], faradiol-3-O-palmitate, faradiol-3-O-myristate, faradiol-3-O-laurate [16], arnidiol-3-O-palmitate, arnidiol-3-O-myristate, arnidiol-3-O-laurate, calenduladiol-3-Opalmitate, calenduladiol-3-O-myristate [17,18], oleanolic acid saponins: calenduloside A-H [19][20][21][22], oleanane triterpene glycoside: calendulaglycoside A, calendulaglycoside A6′-O-n-methyl ester, calendulaglycoside A6'-O-n-butyl ester, calendulaglycoside B, calendulaglycoside B 6′-O-n-butyl ester, calendulaglycoside C, calendulaglycoside C 6′-O-n-methyl ester, calendulaglycoside C 6′-O-n-butyl ester, calenduloside F6′-O-n-butyl ester, calnduloside G6′-O-n-methyl ester [18], glucosides of oleanolic acid (mainly found in roots of grown and senescing plants) I, II, III, VI, VII [23,24], and glucuronides (mainly found in flowers and green parts) F, D, D 2 , C, B and A [25]. One new triterpenic ester of olanane series has been isolated from flowers was cornulacic acid acetate from flowers [26].…”

Marigold Metabolites: Diversity and Separation Methods of Calendula Genus Phytochemicals from 1891 to 2022

“…Therefore, the question of the priority of names for compounds 291 , 293 , 295 , 296 , 300 , and 303 remains open; the use of both variants is legitimate. Of note, the variants of names for glucosides C ( 295 ), D ( 296 ), and F ( 303 ), such as calendulosides H, G, and E, respectively, proposed by Vecherko L.P. et al, who isolated these compounds from C. officinalis in 1975–1976 [ 69 , 74 , 76 , 79 , 80 , 81 ], can be considered as synonyms. Calenduloside F ( 299 ) was isolated and characterized by Vecherko L.P. et al (1975) [ 76 ]; however, the final identification of this compound under the name glucoside D 2 was performed by Vidal-Oliver E. (1989) [ 70 ].…”