Dedicated to Professor Leonard Gross on the occasion of his 70th birthday.Abstract. Let µ G and µ P be a Gaussian measure and a Poisson measure on E * , respectively. Let at and a * t be respectively annihilation and creation operators at a point t ∈ R. In the theory of quantum white noise, it is known that at is a continuous linear operator from Γu(E C ) into itself and a * t is a continuous linear operator from Γu(E C ) * into itself. In paticular, at + a * t and at+a * t +a * t at+I are called the quantum Gaussian white noise and the quantum Poisson white noise, respectively. The main purpose of this work is to realize quantum Gaussian and Poisson white noises in terms of multiple Wiener-Itô integrals, and show that such realizations cannot be achieved by J-transform and its holomorphy, but can be done by S X -transform depending on the exponential function φ X ξ , which determines a unitary isomorphism between Boson Fock space and L 2 (E * , µ X ), X = G, P . In Appendix A, some connections between [6][7] and [9] will be discussed.