Calculation of the dosimetric characteristics of the radiopharmaceutical “<sup>188</sup>re-albumin microspheres” in the body of mice based on pharmacokinetic modeling
A. V. Matveev
Abstract:Purpose. Development of a compartment mathematical model of the kinetics of the radiopharmaceutical “188Re-albumin microspheres” in the body of intact mice and calculation on its basis of the dosimetric characteristics of this drug – accumulated and total absorbed doses.
Material and methods. The objects of the study were serum albumin microspheres labeled with rhenium-188 with a diameter of 10−20 microns and the comparison drug Na188ReO4. Experimental pharmacokinetic data were obtained on mongrel white mice.… Show more
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