Calculation of Pediatric Left Ventricular Mass: Validation and Reference Values Using Real-Time Three-Dimensional Echocardiography

Laser, Kai Thorsten; Houben, Britta Anna; Körperich, Hermann; Haas, Nikolaus A.; Kelter-Klöpping, Andrea; Barth, Peter; Burchert, Wolfgang; Dalla‐Pozza, Robert; Kececioglu, Deniz; Herberg, Ulrike

doi:10.1016/j.echo.2014.11.008

Cited by 14 publications

(25 citation statements)

References 50 publications

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“…7,9 In the pediatric setting, 3DE norms for LV volumes have been calculated in limited sample sizes. 1,6,[11][12][13] We sought to investigate pediatric nomograms for LV volumes by 3DE in a large cohort of healthy children.…”

Section: Three-dimensional Echocardiography Derived Nomograms For Lefmentioning

confidence: 99%

Three-Dimensional Echocardiography Derived Nomograms for Left Ventricular Volumes in Healthy Caucasian Italian Children

Cantinotti

Scalese

Giordano

et al. 2019

Journal of the American Society of Echocardiography

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, discussing leaflets and sinuses as separate components of the root instead of interchangeably referring to both as ''cusps''), including recognizing the deficiencies in commonly used classifications for the congenitally malformed aortic valve. This deficiency includes the often underrecognized unicuspid and unicommissural aortic valve, 2 which was not assessed, or possibly not appreciated, in the given account. Although objective data to support the best methods for 2D assessment and continued monitoring of asymmetric aortic roots in congenitally malformed aortic valves are currently absent, we should nonetheless aim our sights higher. It is now commonplace to view cardiac anatomy in three dimensions using multiple imaging modalities. Ideally, the imager could reliably follow aortic root volumes for a more accurate assessment, especially given that the aortic root dilates not just circumferentially but also longitudinally. 2 In the meantime, would not MRI or computed tomographic 2D areas prove more accurate? Such normative data in adults as assessed by MRI have already been supplied. 4 Could biplane TTE provide similar accuracy in measuring short-axis areas? The work is clearly laid out for improved understanding in assessment of aortic root dimensions, and we are thankful to Vis et al. 1 for pushing forward this topic, which holds clear clinical significance.

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Section: Three-dimensional Echocardiography Derived Nomograms For Lefmentioning

confidence: 99%

Three-Dimensional Echocardiography Derived Nomograms for Left Ventricular Volumes in Healthy Caucasian Italian Children

Cantinotti

Scalese

Giordano

et al. 2019

Journal of the American Society of Echocardiography

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“…This observation has already been confirmed by investigating muscle mass in this age group. 42 Values within the range of the third and 97th percentiles are currently regarded as ''normal''; thus, values less than the third percentile would indicate inadequate flow volume, while values greater than the 97th percentile would be suggestive of hyperperfusion. These centile curves use parameters that express CO but have a distinct dimension.…”

Section: Reference Magnitudes For Vtimentioning

confidence: 99%

Centile Curves for Velocity-Time Integral Times Heart Rate as a Function of Ventricular Length: The Use of Minute Distance Is Advantageous to Enhance Clinical Reliability in Children

Solinski

Klusmeier

Horst

et al. 2018

Journal of the American Society of Echocardiography

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“…Both the training background of the examiner and the exact type or version of hardware and software used dramatically influence 2D echocardiography LVM determinations 14 . Recent software allows the calculation of LVM with RT3DE 2,3,15 . On direct comparison of LVM assessment with M-Mode or 2D echocardiography and RT3DE in healthy children, RT3DE, using both manual and automated algorithms, was superior to M-Mode and 2D measurements with respect to accuracy and reproducibility.…”

Section: Discussionmentioning

confidence: 99%

“…Up to now the gold standard for mass assessment has been cardiac magnetic resonance imaging (CMR) 1 . While standard-formula based mass estimation by 2-dimensional (2D) echocardiography risks inaccuracies, new software developments allow real-time 3-dimensional echocardiography (RT3DE)- based calculation of LVM 2,3 . Since particularly in patients with cardiac disease, e.g ., CHD, clinical decision-making relies more and more on imaging data, the comparability of imaging results often is important not only intrainstitutionally but also interinstitutionally.…”

Section: Introductionmentioning

confidence: 99%

Left ventricular mass estimation by real-time 3D echocardiography favourably competes with CMR in congenital left ventricular disease

Michel

Shabanah

Körperich

et al. 2019

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Assessment of left ventricular mass (LVM) is important in the evaluation of patients with congenital heart disease (CHD) and cardiac magnetic resonance imaging (CMR) is the gold standard. Recent software allows LVM calculation by real-time 3-dimensional echocardiography (RT3DE). We investigated the impact of different software analysis tools on LVM determination by CMR or RT3DE in a cohort of patients with heterogeneous left ventricular (LV) disease. 37 subjects (17 patients, mean age 18.7 y; 20 controls, mean age 13.2 y) underwent CMR and RT3DE. CMR LVM and RT3DE calculations were done using two different LV-analysis software packages for each modality: CMR i) customized software “CMR HDZ”, CMR ii) “CMR ISP”; RT3DE i) “Toshiba”, RT3DE ii) “Tomtec”, 4D LV-Analysis Version 3.1 (built 3.1.0.258661). Intra- and interobserver variabilities were calculated. Only RT3DE-derived LVM showed significant software-dependent differences. RT3DE-derived LVM (both softwares) was significantly higher than CMR-derived LVM (both softwares). The two different methods and four evaluation software packages for LVM assessment were well correlated with each other. Intra- and interobserver variability of LVM as assessed by each single modality or software was low. Despite software dependency and overestimation of RT3DE-assessed LVM by 5 to 10%, RT3DE still competes with the gold standard, CMR, even in patients with various forms of LV disease. The use of optimized software, especially for RT3DE, should improve the accuracy of LVM assessment, overcoming LVM overestimation.

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Calculation of Pediatric Left Ventricular Mass: Validation and Reference Values Using Real-Time Three-Dimensional Echocardiography

Cited by 14 publications

References 50 publications

Three-Dimensional Echocardiography Derived Nomograms for Left Ventricular Volumes in Healthy Caucasian Italian Children

Three-Dimensional Echocardiography Derived Nomograms for Left Ventricular Volumes in Healthy Caucasian Italian Children

Centile Curves for Velocity-Time Integral Times Heart Rate as a Function of Ventricular Length: The Use of Minute Distance Is Advantageous to Enhance Clinical Reliability in Children

Left ventricular mass estimation by real-time 3D echocardiography favourably competes with CMR in congenital left ventricular disease

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