The purpose of this study was to investigate the short-term effects of maize (Zea mays)-fallow rotation, residue management, and soil water on carbon mineralization in a tropical cropping system in Ghana. After 15 months of the trial, maize-legume rotation treatments had significantly (P<0.001) higher levels of potentially mineralizable carbon, C 0 (μg CO 2 -C g −1 ) than maize-elephant grass (Pennisetum purpureum) rotations. The C 0 for maize-grass rotation treatments was significantly related to the biomass input (r=0.95; P=0.05), but that for the maize-legume rotation was not. The soil carbon mineralization rate constant, k (per day), was also significantly related to the rotation treatments (P< 0.001). The k values for maize-grass and maizelegume rotation treatments were 0.025 and 0.036 day −1 respectively. The initial carbon mineralization rate, m 0 (μg CO 2 -C g −1 day −1 ), was significantly (P<0.001) related to the soil water content, θ. The m 0 ranged from 3.88 to 18.67 and from 2.30 to 15.35 μg CO 2 -C g −1 day −1 for maizelegume and maize-grass rotation treatments, respectively, when the soil water varied from 28% to 95% field capacity (FC). A simple soil water content (θ)-based factor, f w , formulated as: f w ¼ qÀq d