Calcium Sodium Phosphosilicate (NovaMin^®): Remineralization Potential

Abstract

The authors declare no conflict of interest. N ovaMin ® is the trade name for a calcium sodium phosphosilicate bioactive glass that has been developed for use in oral health care. Originally developed for the treatment of hypersensitivity by the physical occlusion of dentinal tubules, recent studies have demonstrated a potential for this material to prevent demineralization and/or aid in remineralization of tooth surfaces. The mode of action of this material results from interactions with aqueous solutions. When introduced into the oral environment, the material releases sodium, calcium, and phosphate ions, which then interact with oral fluids and result in the formation of a crystalline hydroxycarbonate apatite (HCA) layer that is structurally and chemically similar to natural tooth mineral. This article will focus on the mechanisms of action of NovaMin and present results from a series of in vitro and in situ studies demonstrating the potential of this material in the areas of remineralization and caries prevention.

Chair Side Application of NovaMin for the Treatment of Dentinal Hypersensitivity- A Novel Technique

“…As the reactions and the deposition of Ca-P complexes continue, this layer crystallizes into hydroxycarbonate apatite (HCA), which is chemically and structurally similar to biological apatite. The combination of the residual calcium sodium phosphosilicate particles and the HCA layer results in the physical occlusion of dentinal tubules, which will relieve hypersensitivity [23].…”

“…In group II VAS score were 6.2, 3.35, 2.9, 2.75 and group III 6.6, 7.0, 7.0, 7.0 respectively. For cold water stimulus in group I VAS score were 5. name for a calcium sodium phosphosilicate bioactive glass that has been developed for use in oral health care [23]. NovaMin precipitates calcium and phosphate and has been used to decrease hypersensitivity by occluding exposed dentinal tubules [24].…”

An In vitro SEM Study on the Effect of Bleaching Gel Enriched with NovaMin on Whitening of Teeth and Dentinal Tubule Occlusion

“…Being originally developed as a bone regenerative material, this compound has been shown to be effective in occluding dentinal tubules physically, through the development of a hydroxyapatite-like mineral layer [10].…”

Influence of prophylaxis paste treatment on the abrasive wear of surface sealants

“…By the findings of the present study it might be concluded that a pre-treatment of dentine with a mineral deposing [9,34] inducing prophylaxis paste (NUPRO Sensodyne) before application of the tested surface sealants does not affect stability and wear resistance of the applied surface sealant (Seal&Protect or K-0184). Furthermore, surface sealants (Seal&Protect and K-0184) provide a stable protective surface layer on dentine, which last for at least 12000 brushing strokes.…”