“…These studies detected elevations in [Ca 2ϩ ] i resulting from stimulation with single odor ligands or odor mixtures (Restrepo et al, 1990(Restrepo et al, , 1993aRestrepo and Boyle, 1991;Sato et al, 1991Sato et al, , 1994Nakamura et al, 1994;Tareilus et al, 1995), forskolin (Sato et al, 1991;Restrepo et al, 1993b), or dialysis of ORNs with cAMP (Nakamura et al, 1994) or IP 3 (Nakamura et al, 1994;Schild et al, 1995). Despite these abundant data, studies to date have not addressed Ca 2ϩ signals in the cilia, the site of odor transduction.…”