Calcium pyrophosphate deposition disease of the spine mimicking septic arthritis

Mazzoni, Daniel; Loch-Wilkinson, Thorbjorn; Stephens, S. D. G.

doi:10.1111/imj.15452

Cited by 1 publication

(1 citation statement)

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“…There is a case report in which a patient with lumbar spinal CPPD was assumed to have osteomyelitis due to increased MRI signal intensity after months of lower back pain and neurological symptoms [12]. An additional report discussed a case of CPPD that presented with elevated inflammatory markers and was initially treated for presumed septic arthritis of the spine [13]. Our patient did not present with any signs or symptoms of infection.…”

Section: Discussionmentioning

confidence: 88%

A Case of Pseudogout Causing Thoracic Myelopathy

Carpenter¹,

Siddique²,

El‐Zammar³

et al. 2022

Cureus

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Calcium pyrophosphate deposition disease is not an uncommon cause of polyarthritis, especially in the elderly. This disease typically affects the appendicular skeleton but may rarely affect the axial skeleton as well. When the axial skeleton is involved, it can lead to numerous neurological signs and can be disabling. We describe a case in which a 68-year-old male presented with on-and-off myelopathy and was thought to have chronic inflammatory demyelinating polyneuropathy. Magnetic resonance imaging of the spine suggested an inflammatory or infectious lesion at the thoracic level. However, after a surgical biopsy, pathologists concluded that calcium pyrophosphate deposition, or pseudogout, was the cause of this patient's neurological symptoms. Pseudogout in the spine, especially the thoracic spine, is exceptionally rare. There are very few additional cases reported. In this report, we review the current literature on existing similar cases, radiological findings, risk factors, and treatments for this condition in hopes of increasing knowledge and awareness of this rare differential.

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Section: Discussionmentioning

confidence: 88%