Calcium phosphates nanoparticles: The effect of freeze-drying on particle size reduction

Piazza, Rodolfo Debone; Pelizaro, Thales A. Garcia; Rodriguez-Chanfrau, Jorge E.; Almirall, Amisel; Veranes-Pantoja, Yaymarilis; Guastaldi, Antônio Carlos

doi:10.1016/j.matchemphys.2019.122004

Cited by 19 publications

(17 citation statements)

References 30 publications

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“…Nonobservance of these conditions leads to precipitation of the calcium orthophosphates with deviations from a given stoichiometric composition. The possibility of formation during the precipitation process of the metastable phases and the additional phase transformations of already precipitated calcium orthophosphates complicates significantly the determination of their optimum synthesis conditions [10,11,[19][20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Calcium Orthophosphates by Chemical Precipitation in Aqueous Solutions: The Effect of the Acidity, Ca/P Molar Ratio, and Temperature on the Phase Composition and Solubility of Precipitates

et al. 2020

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Studies on chemical precipitation of the calcium orthophosphates have shown that their phase compositions do not vary depending on molar ratio Ca/P but are sensitive to solutions acidity and temperature. These are two key factors that determine the phase transformation progress of metastable phases into less soluble precipitates of the phosphates. It was proposed to compare calcium orthophosphates solubility products with calcium cations quantities in their formulas. It was found that there was a linear correlation between calcium orthophosphates specific solubility products and their molar ratios Ca/P if hydroxyapatite and its Ca-deficient forms were excluded from consideration. It was concluded that the relatively large deviations of their solubility products from the found correlation should be thought of as erroneous data. That is why solubility products were changed in accordance with correlation dependence: pKS for hydroxyapatite was 155, pKS for Ca-deficient hydroxyapatites was 114–155. The solubility isotherms, which were calculated on the basis of the corrected pKS values, coincided with the experimental data on solid-phase titration by Pan and Darvell.

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Section: Introductionmentioning

confidence: 99%

Synthesis of Calcium Orthophosphates by Chemical Precipitation in Aqueous Solutions: The Effect of the Acidity, Ca/P Molar Ratio, and Temperature on the Phase Composition and Solubility of Precipitates

et al. 2020

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“…et al, 2009;Basam, et al, 2017). A banda em 1.637 cm-1 corresponde à água absorvida, ocorrendo devido à vibração de alongamento da água livre (Piazza, et al, 2020).…”

Section: Resultsunclassified

Avaliação Estrutural E Morfológica Da Hidroxiapatita Sintetizada Por Pechini/Structural and Morphological Evaluation of Hydroxyapatite Synthesized by Pechini

Carvalho

Almeida

Alves

et al. 2020

BJD

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RESUMO Este trabalho teve como objetivo sintetizar a hidroxiapatita (Hap) via Pechini e avaliar a influência de diferentes razões ácido cítrico/cátions metálicos (AC/CM) nas características dos pós obtidos. As amostras foram caracterizadas por difração de raios X, espectrometria no infravermelho e microscopia eletrônica de varredura. A relação AC/CM de 4:1 favoreceu a formação da cerâmica com maior percentual de HAp, com alta cristalinidade, apresentando uma morfologia constituída por aglomerados.

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“…The size and shape of calcium phosphate particles are critical for biological reactions such as osteoblast proliferation, cellular activity, apoptosis, and macrophage activity [ 65 ]. By choosing different synthetic methods, altering the starting concentration and Ca/P ratio of the precursor can achieve the expected size [ 66 ] and shape of calcium phosphate particles. The gelatin–strontium substituted calcium phosphate composites can be fabricated via coprecipitation in a gelatin solution to form unidirectional porous scaffolds with an oriented microtubular structure [ 67 ].…”

Section: Inorganic Particles Used In Dentistrymentioning

confidence: 99%

Biopolymers Hybrid Particles Used in Dentistry

Chen

Lee

Huang

2021

Gels

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This literature review provides an overview of the fabrication and application of biopolymer hybrid particles in dentistry. A total of 95 articles have been included in this review. In the review paper, the common inorganic particles and biopolymers used in dentistry are discussed in general, and detailed examples of inorganic particles (i.e., hydroxyapatite, calcium phosphate, and bioactive glass) and biopolymers such as collagen, gelatin, and chitosan have been drawn from the scientific literature and practical work. Among the included studies, calcium phosphate including hydroxyapatite is the most widely applied for inorganic particles used in dentistry, but bioactive glass is more applicable and multifunctional than hydroxyapatite and is currently used in clinical practice. Today, biopolymer hybrid particles are receiving more attention as novel materials for several applications in dentistry, such as drug delivery systems, bone repair, and periodontal regeneration surgery. The literature published on the biopolymer gel-assisted synthesis of inorganic particles for dentistry is somewhat limited, and therefore, this article focuses on reviewing and discussing the biopolymer hybrid particles used in dentistry.

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Calcium phosphates nanoparticles: The effect of freeze-drying on particle size reduction

Cited by 19 publications

References 30 publications

Synthesis of Calcium Orthophosphates by Chemical Precipitation in Aqueous Solutions: The Effect of the Acidity, Ca/P Molar Ratio, and Temperature on the Phase Composition and Solubility of Precipitates

Synthesis of Calcium Orthophosphates by Chemical Precipitation in Aqueous Solutions: The Effect of the Acidity, Ca/P Molar Ratio, and Temperature on the Phase Composition and Solubility of Precipitates

Avaliação Estrutural E Morfológica Da Hidroxiapatita Sintetizada Por Pechini/Structural and Morphological Evaluation of Hydroxyapatite Synthesized by Pechini

Biopolymers Hybrid Particles Used in Dentistry

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