Calcium Isotopes

Farkaš, Juraj

doi:10.1007/978-3-319-39193-9_237-1

Cited by 1 publication

(2 citation statements)

References 25 publications

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“…However, many factors influence absorption efficiency, including the bioavailability of the calcium consumed (e.g., foods with high phytic and oxalic acid are usually considered a poor source of bioavailable calcium), calcium requirements, age, and vitamin D status 27–29 . Several isotopic methods have been developed to measure fractional calcium absorption utilizing stable isotopes ( 40 Ca, 42 Ca, 43 Ca, 44 Ca, 46 Ca, and 48 Ca), radioactive isotope tracers ( 45 Ca and 47 Ca), or combinations of both 21,30 . Isotope enrichment in biological specimens is then measured over several days to weeks.…”

Section: Calcium Absorptionmentioning

confidence: 99%

“…[27][28][29] Several isotopic methods have been developed to measure fractional calcium absorption utilizing stable isotopes ( 40 Ca, 42 Ca, 43 Ca, 44 Ca, 46 Ca, and 48 Ca), radioactive isotope tracers ( 45 Ca and 47 Ca), or combinations of both. 21,30 Isotope enrichment in biological specimens is then measured over several days to weeks.…”

Section: Calcium Absorptionmentioning

confidence: 99%

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Calcium status assessment at the population level: Candidate approaches and challenges

Rana

Bourassa

Gomes

et al. 2022

Annals of the New York Academy of Sciences

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Inadequate dietary calcium intake is a global public health problem that disproportionately affects low-and middle-income countries. However, the calcium status of a population is challenging to measure, and there are no standard methods to identify high-risk communities even in settings with an elevated prevalence of a disease caused or exacerbated by low calcium intake (e.g., rickets). The calcium status of a population depends on numerous factors, including intake of calcium-rich foods; the bioavailability of the types of calcium consumed in foods and supplements; and population characteristics, including age, sex, vitamin D status, and genetic attributes that influence calcium retention and absorption. The aim of this narrative review was to assess candidate indicators of population-level calcium status based on a range of biomarkers and measurement methods, including dietary assessment, calcium balance studies, hormonal factors related to calcium, and health outcomes associated with low calcium status. Several promising approaches were identified, but there was insufficient evidence of the suitability of any single indicator to assess population calcium status. Further research is required to develop and validate specific indicators of calcium status that could be derived from the analysis of data or samples that are feasibly collected in population-based surveys.

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Section: Calcium Absorptionmentioning

confidence: 99%