Calcium hydroxide‐loaded nanoparticles dispersed in thermosensitive gel as a novel intracanal medicament
Xavier Roig,
Lyda Halbaut,
Firas Elmsmari
et al.
Abstract:AimDesign, produce and assess the viability of a novel nanotechnological antibacterial thermo‐sensible intracanal medicament This involves encapsulating calcium hydroxide (Ca(OH)2) within polylactic‐co‐glycolic acid (PLGA) nanoparticles (NPs) and dispersing them in a thermosensitive gel (Ca(OH)2‐NPs‐gel). In addition, perform in vitro and ex vivo assessments to evaluate tissue irritation and penetration capacity into dentinal tubules in comparison to free Ca(OH)2.MethodologyReproducibility of Ca(OH)₂‐NPs was c… Show more
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