‘Calcium fluoride-like’ material formed in partially demineralized human enamel in vivo owing to the action of fluoridated toothpastes

Arends, J; Reintsema, Harry; Dijkman, Tg

doi:10.3109/00016358809004787

Cited by 20 publications

(15 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The morphol ogy of these crystals closely approached that of pure CaF2 and differed from that reported previously in the dental literature [Nelson et al. 1983;Arends et al, 1988;Rolla and Saxegaard. 1990] for CaF:-like precipitates on enam el.…”

Section: Discussioncontrasting

confidence: 54%

Calcium Fluoride Formation on Sound Enamel Using Fluoride Solutions with and without Lactate

et al. 1994

View full text Add to dashboard Cite

The formation of calcium (Ca) fluoride (CaF₂) on bovine enamel blocks during clinically relevant treatment times using neutral fluoride (F) solutions (0.26mol/l F) with and without 0.1mol/l lactate was investigated. Uncoated and pellicle-coated blocks were evaluated for alkali-soluble (1 mol/l KOH, three consecutive 24-hour treatments) Ca, PO₄, and F after treatment by the F solutions for 0, 5, 15, 30, and 60 min. There was an overall time-related increase in F recovery, while Ca tended to remain at baseline levels. Less F was recovered from the pellicle-coated blocks. The addition of lactate to the F treatment solution did not result in an overall increase in alkali-soluble F recovery, but did result in the formation of cuboidal shaped crystals which closely approached the morphology of pure CaF₂. A 1:2 stoichiometric ratio Ca:2F (mohmol) was not established based on chemical analyses. The ultra-structural and elemental composition of surface deposits on the samples, as determined using scanning electron microscopy, X-ray diffraction, and energy-dispersive spectroscopy, established the presence of CaF₂ after 24-hour F treatments; however, it was not possible to directly demonstrate the formation of CaF₂ after clinically relevant treatment times.

show abstract

Section: Discussioncontrasting

confidence: 54%

Calcium Fluoride Formation on Sound Enamel Using Fluoride Solutions with and without Lactate

et al. 1994

View full text Add to dashboard Cite

show abstract

“…In this study, the chelating action of citric acid (soft drink) may have reduced the availability of calcium in the enamel [Low and Alhuthali, 2008] that would be a source for deposition of CaF 2 -like material with fluoridated toothpaste. The artificial saliva used has a lower concentration of calcium in relation to human saliva, which influences the deposition of calcium fluoride [Arends et al, 1988]. In these unfavorable conditions, the toothpaste with a higher concentration of fluoride produces better results ( table 1 ).…”

Section: Discussionmentioning

confidence: 99%

Effect of Different Fluoride Concentrations of Experimental Dentifrices on Enamel Erosion and Abrasion

et al. 2010

View full text Add to dashboard Cite

It has been suggested that fluoride products are able to reduce erosive tooth wear. Thus, the purpose of this in vitro study was to evaluate the effect of dentifrices with different fluoride concentrations as well as of a low-fluoridated dentifrice supplemented with trimetaphosphate (TMP) on enamel erosion and abrasion. One hundred twenty bovine enamel blocks were assigned to the following experimental dentifrices: placebo, 1,100 µg F/g, 500 µg F/g plus 3% TMP and 5,000 µg F/g. The groups of enamel blocks were additionally subdivided into conditions of erosion (ERO) and of erosion plus abrasion (ERO + ABR). For 7 days, the blocks were subjected to erosive challenges (immersion in Sprite® 4 times a day for 5 min each time) followed by a remineralizing period (immersion in artificial saliva between erosive challenges for 2 h). After each erosive challenge, the blocks were exposed to slurries of the dentifrices (10 ml/sample for 15 s). Sixty of the blocks were additionally abraded by brushing using an electric toothbrush (15 s). The alterations of the enamel were quantified using the Knoop hardness test and profilometry (measurements in micrometers). The data were analyzed using a 2-way ANOVA test followed by a Bonferroni correction (p < 0.05). In in vitro conditions, the 5,000 µg F/g and 500 µg F/g plus 3% TMP dentifrices had a greater protective effect when compared with the 1,100 µg F/g dentifrice, under both ERO and ERO + ABR conditions. The results suggest that dentifrices alone are not capable of completely inhibiting tooth wear.

show abstract

“…Generally, following a single topical treatment of all buccal tooth surfaces in the mouth, the calcium-fluoride-like salt is dissolved to such a level within 24 hours after the treatment that the fluoride concentration in mixed saliva has then returned to normal values . Recently, CaF2 has gained renewed interest (R0lla, 1988;Christoffersen et al, 1988;Arends et al, 1988;Arends and Christoffersen, 1990;Margolis and Moreno, 1990;White and Nancollas, 1990). No really solid data describe the dissolution kinetics of calcium fluoride formed in inaccessible pores of natural lesions, but a much longer dissolution period may be expected.…”

Section: The Effect Of Fluoride On Erupted Teethmentioning

confidence: 97%

Dental Tissue Effects of Fluoride

Fejerskov¹,

Larsen²,

Richards³

et al. 1994

Adv Dent Res.

204

149

View full text Add to dashboard Cite

It is now well-established that a linear relationship exists between fluoride dose and enamel fluorosis in human populations. With increasing severity, the subsurface enamel all along the tooth becomes increasingly porous (hypomineralized), and the lesion extends toward the inner enamel. In dentin, hypomineralization results in an enhancement of the incremental lines. After eruption, the more severe forms are subject to extensive mechanical breakdown of the surface. The continuum of fluoride-induced changes can best be classified by the TF index, which reflects, on an ordinal scale, the histopathological features and increases in enamel fluoride concentrations. Human and animal studies have shown that it is possible to develop dental fluorosis by exposure during enamel maturation alone. It is less apparent whether an effect of fluoride on the stage of enamel matrix secretion, alone, is able to produce changes in enamel similar to those described as dental fluorosis in man. The clinical concept of post-eruptive maturation of erupting sound human enamel, resulting in fluoride uptake, most likely reflects subclinical caries. Incorporation of fluoride into enamel is principally possible only as a result of concomitant enamel dissolution (caries lesion development). At higher fluoride concentrations, calcium-fluoride-like material may form, although the formation, identification, and dissolution of this compound are far from resolved. It is concluded that dental fluorosis is a sensitive way of recording past fluoride exposure because, so far, no other agent or condition in man is known to create changes within the dentition similar to those induced by fluoride. Since the predominant cariostatic effect of fluoride is not due to its uptake by the enamel during tooth development, it is possible to obtain extensive caries reductions without a concomitant risk of dental fluorosis.

show abstract

‘Calcium fluoride-like’ material formed in partially demineralized human enamel in vivo owing to the action of fluoridated toothpastes

Cited by 20 publications

References 14 publications

Calcium Fluoride Formation on Sound Enamel Using Fluoride Solutions with and without Lactate

Calcium Fluoride Formation on Sound Enamel Using Fluoride Solutions with and without Lactate

Effect of Different Fluoride Concentrations of Experimental Dentifrices on Enamel Erosion and Abrasion

Dental Tissue Effects of Fluoride

Contact Info

Product

Resources

About