Calcium and vitamin D in obesity

Song, Qingming; Сергеев, И. Н.

doi:10.1017/s0954422412000029

Cited by 86 publications

(100 citation statements)

References 120 publications

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“…Preliminary studies in rats suggest that the supplementation with elevated doses of calcium and vitamin D reduce the weight and fat mass in obese rats. Studies in humans are necessary for the evaluation of the efficiency of vitamin D in the treatment of obesity (166).…”

Section: H) Vitamin D and Physical And Cognitive Function Of The Elderlymentioning

confidence: 99%

Recomendações da Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) para o diagnóstico e tratamento da hipovitaminose D

Maeda

Borba

Camargo

et al. 2014

Arq Bras Endocrinol Metab

223

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Objective: The objective is to present an update on the diagnosis and treatment of hypovitaminosis D, based on the most recent scientific evidence. Materials and methods: The Department of Bone and Mineral Metabolism of the Brazilian Society of Endocrinology and Metabology (SBEM) was invited to generate a document following the rules of the Brazilian Medical Association (AMB) Guidelines Program. Data search was performed using PubMed, Lilacs and SciELO and the evidence was classified in recommendation levels, according to the scientific strength and study type. Conclusion: A scientific update regarding hypovitaminosis D was presented to serve as the basis for the diagnosis and treatment of this condition in Brazil.

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Section: H) Vitamin D and Physical And Cognitive Function Of The Elderlymentioning

confidence: 99%

Recomendações da Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) para o diagnóstico e tratamento da hipovitaminose D

Maeda

Borba

Camargo

et al. 2014

Arq Bras Endocrinol Metab

223

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“…Vitamin D status has been linked to several cancers and obesity in numerous observational and a limited number of mechanistic studies [6,[11][12][13][14][15][16][17][18][19][20]. Vitamin D deficiency/insufficiency has been associated with the increased risk of colorectal, breast, ovarian, prostate, pancreatic, skin, and other types of cancer as well as obesity; however, causality in these associations remains unproven [4,6,[11][12][13][14][15][16][17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

Vitamin D-mediated apoptosis in cancer and obesity

Сергеев

2014

Hormone Molecular Biology and Clinical Investigation

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Low vitamin D status has been associated with increased risk of several cancers and obesity; concurrently, obesity and cancer have been linked to impaired vitamin D status. In both cancer and obesity, selective elimination of cancer cells and adipocytes can result in decreasing tumor size and a long-term reduction in adipose tissue mass. These effects can be achieved through induction of apoptotic cell death. -dependent apoptotic proteases as promising targets for discovery of new therapeutic and preventive agents for cancer and obesity. The concept of maintaining an increased vitamin D status for protecting against cancer and decreasing adiposity also warrants further evaluation.

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“…It was also found that vitamin D3 was effective in weight loss by increasing fat oxidation after meals (10). Likewise, Song et al obtained similar findings of Soares et al However, they reported a different mechanism for weight reduction impact of vitamin D. They concluded a role for vitamin D to regulate of fat cell death and lipid metabolism (11). Similarly, Salehpour et al investigated the association between vitamin D deficiency and obesity.…”

Section: Introductionmentioning

confidence: 77%

Therapeutic impact of cholecalciferol in patients with psychiatric disorders receiving olanzapine

Kaviyani¹,

Bahadoram²,

Houshmand³

et al. 2017

J Parathyr Dis

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Introduction: Psychiatric disorders such as schizophrenia require appropriate treatment. Second-generation antipsychotics, including olanzapine, are administered as an appropriated treatment for these disorders. However, this drug has several complications, such as obesity and increased waist circumference which reduces the acceptance of the treatment. Objectives: The aim of this study was to investigate the effects of vitamin D3 therapy on waist circumference caused by olanzapine. Patients and Methods: In this randomized clinical trial, 50 hospitalized women with psychiatric disorders receiving olanzapine were divided into two groups of intervention and control groups. Before the intervention, the waist circumference, hip circumference, and waist-hip ratio were measured. Then, for 12 weeks, the intervention group received vitamin D3 and the control group received paraffin as the placebo, one pearl every 2 weeks. Waist circumference, hip circumference, and waist-hip ratio were re-measured and the collected data were analyzed by pair t test. Results: Our findings showed that there is a significant decrease in waist circumference and waist-hip ratio in intervention group (P < 0.001). However, these changes were not significant in the placebo group. Hip circumference was not changed significantly in both groups. Conclusion: Vitamin D can be administered concomitant with 0lanzapine to improve side effects of olanzapine such as increasing waist circumference.

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Calcium and vitamin D in obesity

Cited by 86 publications

References 120 publications

Recomendações da Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) para o diagnóstico e tratamento da hipovitaminose D

Recomendações da Sociedade Brasileira de Endocrinologia e Metabologia (SBEM) para o diagnóstico e tratamento da hipovitaminose D

Vitamin D-mediated apoptosis in cancer and obesity

Therapeutic impact of cholecalciferol in patients with psychiatric disorders receiving olanzapine

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