Calcium and magnesium deficiency-induced atrophy of muscle and calcium accumulation in the spinal cord

Nakagawa, Shiro; Suematsu, Chiharu; Kumamoto, Tetsuzo; Ito, Naotaka

doi:10.1007/bf02003765

Cited by 2 publications

(1 citation statement)

References 7 publications

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“…It is well known that minerals play an important role in muscle metabolism and muscle function (Table 2). Calcium and magnesium deficiency induces muscle atrophy in Wistar rats [49]. The fourth Korea National Health and Nutrition Examination Survey data showed that daily calcium intake was significantly lower (2.7%) in subjects with sarcopenia than in those without (6.3%) and there is a strong inverse association between daily calcium intake and sarcopenia in non-obese, older Korean adults [50].…”

Section: Mineralsmentioning

confidence: 99%

Nutraceuticals in the Prevention and Treatment of the Muscle Atrophy

Wang

Liu²,

Quan

et al. 2021

Nutrients

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Imbalance of protein homeostasis, with excessive protein degradation compared with protein synthesis, leads to the development of muscle atrophy resulting in a decrease in muscle mass and consequent muscle weakness and disability. Potential triggers of muscle atrophy include inflammation, malnutrition, aging, cancer, and an unhealthy lifestyle such as sedentariness and high fat diet. Nutraceuticals with preventive and therapeutic effects against muscle atrophy have recently received increasing attention since they are potentially more suitable for long-term use. The implementation of nutraceutical intervention might aid in the development and design of precision medicine strategies to reduce the burden of muscle atrophy. In this review, we will summarize the current knowledge on the importance of nutraceuticals in the prevention of skeletal muscle mass loss and recovery of muscle function. We also highlight the cellular and molecular mechanisms of these nutraceuticals and their possible pharmacological use, which is of great importance for the prevention and treatment of muscle atrophy.

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Section: Mineralsmentioning

confidence: 99%