Calcifying epithelial odontogenic tumor (Pindborg tumor) without calcification: A rare entity

Abstract

The calcifying epithelial odontogenic tumor is a rare benign odontogenic tumor that was first described by Pindborg in 1955. It accounts for less than 1% of all odontogenic neoplasms. The tumor is characterized histologically by the presence of polygonal epithelial cells, calcification, and eosinophilic deposits resembling amyloid. Noncalcifying Pindborg tumor is very rare and only three cases have been documented in the English language literature so far. We present an additional case of noncalcifying Pindborg tumor and review the previously reported cases. Because noncalcifying Pindborg tumor is believed to be an aggressive variant, a definitive resection of the tumor with tumor-free surgical margins and long-term follow-up is recommended.

Intraosseous calcifying epithelial odontogenic (Pindborg) tumor: A rare entity

“…It also concurrently erodes bone and thus, the lesion often appears as mixed radiolucent-radiopaque mass with many small irregular trabeculae traversing the radiolucent area giving a characteristic “driven snow” appearance on the radiograph due to scattered flecks of calcification. [ 1 2 5 10 15 ] The present case seems to support this appearance. The tumor most commonly appears as either a diffuse or a well-circumscribed unilocular radiolucent area.…”

“…Calcifying epithelial odontogenic tumor (CEOT), also known as a Pindborg tumor, is a locally aggressive, rare benign odontogenic neoplasm of epithelial origin that accounts for <1% of all odontogenic tumors. [ 1 2 3 4 5 ] It was first described by a Dutch pathologist Jens Jorgen Pindborg in 1955. [ 2 ] He, in 1958, grouped the tumor as a distinct histopathologic entity.…”

Jaw lesions associated with impacted tooth: A radiographic diagnostic guide

“…12 38 These tumors usually present as a slow-growing painless mass that can lead to expansion of the jaws. 12 40 The two most prevalent radiographic features of calcifying epithelial odontogenic tumor are pericoronal radiolucency, as well as radiolucent areas with diffuse opacities. A mixed radiolucent-radiopaque pattern is the most common pattern (65%), followed by radiolucent areas (32%), and radiopaque cases (3%) ( Fig.…”

Calcifying Epithelial Odontogenic Tumor

“…The calcifying epithelial odontogenic tumor (CEOT) or Pindborg tumor is a rare benign epithelial odontogenic neoplasm [ 1 , 2 ], with approximately 200 reported cases in the literature [ 3 ]. In general it occurs as a slow-growing tumor [ 4 ], associated with an impacted tooth in the posterior mandibular region [ 5 , 6 ]. This occurs predominantly between the fourth and fifth decades of life, with no preference of gender [ 2 – 4 ].…”

“…In general it occurs as a slow-growing tumor [ 4 ], associated with an impacted tooth in the posterior mandibular region [ 5 , 6 ]. This occurs predominantly between the fourth and fifth decades of life, with no preference of gender [ 2 – 4 ]. Radiographically, CEOT is characterized by a uni- or multilocular lesion that often shows a mixed radiolucent-radiopaque pattern [ 6 ].…”