Calcified Amorphous Tumor of the Heart: Case Report and Review of the Literature

Cardiac calcified amorphous tumors: CT and MRI findings

“…In contrast, Lewin et al (2) and Kubato et al (6) described cardiac CAT as late-phase chronologic changes in a thrombus and reported abnormal calcium metabolism due to renal dysfunction and suggested that inflammation associated with hemodialysis may contribute to rapid growth and pathologic changes. Histologic findings in our patients were thrombus with angiogenesis, fibrin, and calcium deposition, as reported in a literature review (4)(5)(6)(7)14).…”

Calcified amorphous tumor of the heart in a hemodialysis patient

“…CATs have been found in all cardiac chambers and even in the sinus of Valsalva, most commonly on the mitral valve or annulus . Although the pathogenesis of CAT remains poorly understood, MAC‐related CAT is usually associated with end‐stage renal disease (ESRD) and hemodialysis and is suspected to be an atypical variant of cardiac CAT.…”

“…As MAC more commonly affects the posterior annulus than the anterior annulus, MAC‐related CAT frequently attaches to the posterior mitral annulus. Natural history and growth rate of CAT are largely unknown, but may be relatively fast, especially in MAC‐related CAT . Indeed, the masses grew up dramatically during the last 1 year before surgery in the present case.…”

Ancient cardiac myxomas – another point of view in the light of tetraspanins

“…Myxoma is diagnosed conclusively based exclusively on histopathological evaluation no matter how detailed the radiological report may be, bearing in mind that clinical signs, e.g. embolisation-related cerebral infarction and cardiac ischemia are not exclusively specific for each of these neoplasms [39,40,41]. We present in Fig.…”