Calcific lesions are the last frontier of endovascular therapies

Abstract

Key Points This study brings new important insights on the role of drug‐coated balloons for calcific lesions management in peripheral interventions, being this therapeutic option less performant in longer calcifications, as assessed by PACSS methodology. The role of intravascular imaging and atherectomy devices, and if these rules can be applied also to coronary arteries is still not understood. Calcified arteries are the last frontier of endovascular interventions, and ongoing adequately powered studies will hopefully shed light on the best treatment for this complex scenario.